TP53

Species Gene alias ENTREZ ID Ensembl ID UniProt ID Pfam ID Orthologs
Homo sapiens BCC7,BMFS5,LFS1,P53,TRP53 7157 ENSG00000141510 K7PPA8,P04637,Q53GA5,H2EHT1,A0A087X1Q1,A0A087WXZ1,A0A087WT22 PF00870,PF07710,PF18521,PF08563 -
Summary
  • The relevant cell types for TP53 are ranked by evaluation of supported literature, expression enrichment and conservation.
  • Show value
    No. of publications
    >=
    log2FC
    The median log2 fold-change of expression (FDR < 0.05) in a cell cluster to that in all other cells among the available scRNA-seq samples

    >=
    Highly expressed ratio
    Number of samples in which genes are more highly expressed in this cell type compared to other cell types (log2FC > 0.25, FDR < 0.05) divided by number of total samples for the cell type

    >=
    Specificity score
    The median cell specificity score (calculated by Jensen-Shannon divergence score, ranging from 0 to 1) among available scRNA-seq samples

    >=
    Conservation score
    Number of ortholog genes which are also reported as cell markers for this cell type in other species

    >=
    		Total
Cell marker expression enrichment
This panel shows the top cell types in which this marker is highly specifically expressed (with significant high fold change between this cell type and others in relevant scRNA-seq samples; FDR < 0.05).
Rank by highly expressed ratio
Cell type No. of total samples (E) No. of highly expressed samples (HE, FDR<0.05) Highly expressed ratio (HE/E)
Species Sample Condition Cell type log2FC Pct.cell type
The expression percentage of this gene in this cell type
Pct.others
The expression percentage of this gene in other cell types
P value FDR
Species Sample Condition Cell type Specificity score
Jensen-Shannon (JS) divergence score (0-1) is calculated to quantify the cell type specificity of one cell marker (Cabili MN et al., 2011 ).