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  • Glioblastoma
    • Classification:Glioblastoma
    Brain Disease:Glioma
    Categories:Neoplasms, Nerve Tissue
    Description:A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
    Gene Symbol Type Potential PMID
    ACSS2 mRNA
    Therapy
    		 25525878 28820290
    ACVR1 mRNA
    Diagnosis
    Therapy
    		 24705251 24705254 24840074 32142668
    ADAM29 mRNA
    Therapy
    		 28854171
    ADGRA2 mRNA
    Therapy
    		 28288111
    ADSL mRNA
    Prognosis
    		 28346452
    ADSS2 mRNA
    Prognosis
    		 28346452
    ALDH1A1 mRNA
    Prognosis
    Therapy
    		 29728268
    ALDH1A3 mRNA
    Prognosis
    Therapy
    		 29728268
    ALKBH5 mRNA - 28344040 28399407
    AMPB mRNA
    Diagnosis
    		 24316889
    APNG mRNA
    Prognosis
    		 23817353
    ARL13B mRNA
    Therapy
    		 33855339
    ATF3 mRNA
    Prognosis
    		 23746971
    ATF5 mRNA
    Therapy
    		 20495567
    ATG4B mRNA
    Prognosis
    Therapy
    		 29232556
    ATRX mRNA - 24705251
    AVIL mRNA - 32651364
    BCAN mRNA - 29654229
    BCL2L1 mRNA
    Therapy
    		 29057925
    BCL2L12 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 19806145
    BCOR mRNA - 28966033
    BMI1 mRNA
    Therapy
    		 29035367
    BMPR1B mRNA
    Therapy
    		 18167341
    BMX mRNA
    Therapy
    		 21481791
    BRAF mRNA - 30742119
    C1QL1 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 33390587
    C5AR1 mRNA
    Prognosis
    		 32179921
    CAVIN1 mRNA
    Therapy
    		 33140095
    CBX7 mRNA
    Prognosis
    		 23746971
    CCL5 mRNA
    Prognosis
    		 31593589
    CCN4 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 32541784
    CCND1 mRNA
    Therapy
    		 25939062
    CD24 mRNA
    Prognosis
    Therapy
    		 29180699
    CD274 mRNA
    Prediction
    		 26323609 29532035 32860047
    CD44 mRNA
    Prognosis
    Therapy
    		 21156287 23993863 24607407
    CD8A mRNA
    Prognosis
    		 29763623
    CDK4 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 18772396
    CDK5 mRNA
    Prognosis
    		 31488827
    CDKN2A mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 18772396 27515827 29654229
    CDKN2B mRNA
    Prediction
    		 19578366
    CDLA-4 mRNA
    Therapy
    		 26658052
    CDR1-AS mRNA
    Therapy
    Prediction
    		 32894144
    CDR1-AS (ciRS-7) circRNA
    Prognosis
    Therapy
    		 32894144
    CEBPB mRNA
    Prognosis
    Therapy
    		 21811295
    CHEK2 mRNA
    Therapy
    		 21156285
    circ-ASAP1 circRNA
    Therapy
    		 32926734
    circ-E-Cad circRNA
    Therapy
    		 33664496
    circ-EGFR circRNA
    Prognosis
    		 33325513
    circ-FOXO3 circRNA
    Therapy
    Prediction
    		 31504797
    circ-LINC-PINT circRNA
    Therapy
    		 30367041
    circ-MAPK4 circRNA
    Therapy
    		 31992303
    circ-MMP9 circRNA
    Therapy
    		 30470262
    CLOCK mRNA
    Therapy
    		 31919052
    CPEB4 mRNA - 22138752
    CREB1 mRNA
    Therapy
    		 25084773
    CSF-1R mRNA
    Therapy
    		 27199435
    CTNNB1 mRNA
    Therapy
    		 29313411
    CTNND2 mRNA
    Diagnosis
    Therapy
    		 23917401 24071842
    CXCL8 mRNA
    Therapy
    		 28650441
    CXCR3-A mRNA - 29146996
    DLL3 mRNA
    Diagnosis
    Prognosis
    Therapy
    		 16530701
    DPF2 mRNA
    Therapy
    		 29373718
    EGFR mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 20129251 20399149 20531430 21102433 22059152 22137795 22588882 23533263 23707073 23917401 24071842 24135276 24135280 24893890 25092745 25855404 26455392 27515827 27576873 28604685 29040782 29741745 29990498
    EGFRVIII mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 23533263 23707073 24135276 28604685 29377763 29509936 29617843 29660021 29746665
    eIF4A3 mRNA
    Therapy
    		 30470262
    ELOVL2 mRNA
    Therapy
    		 31201181
    ENO1 mRNA
    Therapy
    		 22895339
    ENO2 mRNA
    Therapy
    		 22895339
    EPHA2 mRNA
    Diagnosis
    		 23238013
    EPHA3 mRNA
    Therapy
    		 23410976
    ERBB2 mRNA
    Therapy
    		 29509936
    ERN1 mRNA
    Therapy
    		 29311133
    EZH2 mRNA
    Therapy
    		 23684459 23847365 28263309 29035367
    F11R mRNA
    Therapy
    		 32592484
    FAS mRNA
    Therapy
    		 18328427
    FGFR mRNA
    Therapy
    		 22837387
    FGFR1 mRNA
    Diagnosis
    Prognosis
    Therapy
    		 23583981 24553142 25525250 25939062 28263307 28263309 28486100 28854171 30402543 33545065
    FOXM1 mRNA
    Therapy
    		 22014565 28344040 28399407 32651364
    FOXM1-AS mRNA - 28344040
    FOXM1-AS1 mRNA - 28399407
    FOXO mRNA - 15084259
    FTH1 mRNA
    Therapy
    		 26461092
    FTL mRNA
    Therapy
    		 26461092
    G34 mRNA
    Therapy
    		 23658294
    GFAP mRNA - 25366110
    GMPS mRNA
    Prognosis
    		 28346452
    H3-3A mRNA
    Diagnosis
    Prognosis
    Therapy
    		 23079654 23658294 23817351 24183680 29016894 29763623
    H3-3B mRNA - 26678332
    has-mir-10b miRNA
    Therapy
    		 26881967
    has-mir-589–3p miRNA
    Therapy
    		 29267965
    HAVCR2 mRNA
    Therapy
    		 18006747
    HNF4A mRNA
    Diagnosis
    Prognosis
    		 25050814
    HNRNPA1 mRNA - 23707073
    hsa-let-7 miRNA - 32651364
    hsa-mir-124a miRNA
    Therapy
    		 29016843
    hsa-mir-138 miRNA
    Therapy
    		 26658052
    hsa-mir-145 miRNA - 26374689
    hsa-mir-155-3p miRNA - 27163161
    hsa-miR-181a-5p miRNA
    Prediction
    		 32098627
    hsa-mir-1908 miRNA
    Prognosis
    Therapy
    Prediction
    		 26265437
    hsa-mir-29c miRNA - 26450587
    hsa-mir-320 miRNA
    Diagnosis
    Prognosis
    Therapy
    		 24435880
    hsa-mir-34a miRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 22750848
    hsa-mir-574-3p miRNA
    Diagnosis
    Prognosis
    Therapy
    		 24435880
    hsa-mir-7 miRNA
    Therapy
    		 29016934
    HSV-Tk mRNA
    Diagnosis
    Prognosis
    Therapy
    		 24061435
    Huntingtin mRNA
    Diagnosis
    Prognosis
    		 25050814
    ICOSLG mRNA
    Diagnosis
    Therapy
    		 31634400
    IDH1 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 18772396 20129251 20399149 20531430 22343889 23079654 23817351 27571882 29180699 29474647 30069053
    IDH2 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 20531430 29474647
    IDH3A mRNA
    Diagnosis
    Prognosis
    		 25050814
    IGF1R mRNA - 26136493
    IL-13Rα2 mRNA
    Therapy
    		 29203859
    IL13 mRNA
    Prognosis
    Therapy
    		 29509936
    IL6 mRNA - 27163161
    IMPDH1 mRNA
    Prognosis
    		 28346452
    IRS1 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 18772396
    JAG1 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 30559479
    JMJD6 mRNA
    Therapy
    		 28678782
    K27 mRNA
    Therapy
    		 23658294
    KDM6B mRNA
    Therapy
    		 31085178
    KDR mRNA - 26420897
    KMT5B mRNA
    Therapy
    		 29967352
    LDLR mRNA
    Therapy
    		 22586629
    LIF mRNA
    Therapy
    		 19345330
    LIN28B mRNA
    Prognosis
    		 32651364
    lncGRS-1 lncRNA
    Therapy
    		 32234056
    LY6K mRNA
    Prognosis
    		 32055849
    LZTR1 mRNA
    Diagnosis
    Therapy
    		 23917401 24071842
    MALAT1 lncRNA
    Therapy
    		 29202181
    MARCO mRNA
    Therapy
    		 32847614
    MBNL1 mRNA
    Therapy
    		 26881967
    MBNL2 mRNA
    Therapy
    		 26881967
    MBNL3 mRNA
    Therapy
    		 26881967
    MDM2 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 18772396
    MDM4 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 18772396
    MERTK mRNA
    Therapy
    		 28605477
    MET mRNA
    Diagnosis
    Prognosis
    Therapy
    		 22137795 27748748 28097324 30343896
    METEX14 mRNA
    Prognosis
    Therapy
    		 30343896
    MGMT mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 19997073 20531430 22430106 23147854 25822375 27571882 28097324 29165638 29474647 29660006 29741745 32813021
    MKI67 mRNA
    Therapy
    		 25939062
    MMP1 mRNA
    Prognosis
    Therapy
    		 29990498
    mTOR mRNA - 28648777
    MTORC2 mRNA
    Prognosis
    Therapy
    		 22145100 24140020
    MYB mRNA
    Therapy
    		 23583981
    MYC mRNA
    Diagnosis
    Prognosis
    		 23707073 25050814
    MYCN mRNA
    Therapy
    		 23658294
    NF1 mRNA
    Prognosis
    Therapy
    		 20129251 20399149 28697342 30069053 32847614
    NgR1 mRNA
    Diagnosis
    Prognosis
    Therapy
    		 33479772
    NOS2 mRNA
    Prognosis
    		 21729780
    NOTCH1 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 21102433 30559479 33579922
    NR2E1 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 26838672
    NTRK1 mRNA - 24705251 29654229
    OLIG2 mRNA
    Therapy
    		 27165742 33539525
    OSMR mRNA
    Therapy
    		 27227363 32807793
    PBK mRNA - 26081429
    PDCD1 mRNA
    Diagnosis
    Therapy
    		 26658052 30742122 32071302
    PDCD10 mRNA - 26254477
    PDGF mRNA - 17292826
    PDGFA mRNA
    Diagnosis
    		 25117714
    PDGFRA mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 20129251 22137795 22750848 24705254 27515827 29180699
    PDGFRB mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 20531430
    PFKP mRNA
    Diagnosis
    		 29038421
    PHF5A mRNA
    Therapy
    		 23847366
    PIK3CA mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 16697955 18772396 30069053
    PIK3R1 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 18772396
    PLXNB2 mRNA
    Therapy
    		 29100074
    PPAT mRNA
    Prognosis
    		 28346452
    PRC2 mRNA
    Therapy
    		 23715325
    PRMT5 mRNA
    Therapy
    		 33579912
    PROM1 mRNA
    Therapy
    		 17051156
    PRPS1 mRNA
    Prognosis
    		 28346452
    PTEN mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 16530701 18772396 18948956 20385361 20399149 21397851 22000015 25117714 27515827 29654229 30742119
    PTPN11 mRNA - 26617336 30742119
    PTPRZ1 mRNA
    Prognosis
    Therapy
    		 30343896
    RanBP6 mRNA
    Therapy
    		 29229958
    RB1 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 18772396 21397851 27515827
    RNU6-1 mRNA
    Diagnosis
    Therapy
    		 24435880
    RSRC1 mRNA
    Therapy
    		 26881967
    RTEL1 mRNA
    Prediction
    		 19578366
    RTK mRNA - 25855404
    SART3 mRNA
    Therapy
    		 26881967
    SEPTIN14 mRNA - 23917401
    SLC2A3 mRNA
    Therapy
    		 29198914
    SMAD4 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 22750848
    SOX10 mRNA
    Therapy
    		 33846316
    SOX2-OT lncRNA
    Therapy
    		 29132362
    SPRY2 mRNA
    Prognosis
    Therapy
    		 29635363
    SRRT mRNA
    Therapy
    		 32532977
    SSOs mRNA - 30329087
    STAT3 mRNA
    Prognosis
    Therapy
    		 21811295
    TACC mRNA
    Therapy
    		 22837387
    TEAD1 mRNA - 30275445
    TERC mRNA
    Prognosis
    		 24908248
    TERF1 mRNA - 29136505
    TERT mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 25140036 26957363 27571882 30069053 32882013
    TET3 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 26838672
    TG2 mRNA
    Therapy
    		 27591334
    TGFB1 mRNA
    Therapy
    		 19345322 25084773 32813021
    TLR4 mRNA
    Prognosis
    Therapy
    		 28089910
    TNF mRNA
    Therapy
    		 28650441
    TNFAIP3 mRNA
    Therapy
    		 22585859
    TNFRSF12A mRNA - 29897522
    TNFSF10 mRNA
    Diagnosis
    		 22197831
    TP53 mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 10973261 18772396 18948956 20399149 21397851 24705251 27515827 29654229 31400201
    TP73 mRNA
    Diagnosis
    Therapy
    		 31763674
    TRIM22 mRNA
    Prediction
    		 32814880
    TRIM24 mRNA
    Therapy
    		 29129908
    TRP53 mRNA
    Therapy
    		 29107533
    TSPO mRNA - 31563962
    USP15 mRNA
    Therapy
    		 22344298
    VEG mRNA - 29625067
    VEGFA mRNA
    Diagnosis
    Prognosis
    Therapy
    Prediction
    		 19806145 21102434 22789536 27576873
    VEGFC mRNA
    Therapy
    		 31942068
    W1 mRNA - 29982740
    WEE1 mRNA
    Therapy
    		 29016926
    WNT5A mRNA
    Therapy
    		 27863244
    WWTR1 mRNA
    Therapy
    		 33172899
    YY1AP1 mRNA
    Therapy
    		 33172899
    ZFAND3 mRNA
    Therapy
    		 33311477

    Associated Drugs