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Genes
AMPB
Summary
Diseases
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Specific Gene
Omics Signature
Summary
Gene Symbol:
AMPB
Alias:
_
External Link:
GeneCards
Diseases
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Gene Symbol
Disease
Type
PMID
Source
Gene Symbol
Disease
Type
PMID
Source
AMPB
Glioma
mRNA
24316889
-
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Drugs
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Disease
Target
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PMID
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Specific Gene
Brain Specific Gene
Brain-Region Specific Gene
Brain Specific Protein
Cerebrospinal Fluid Protein
Cell Marker
Omics Signature (Glioma)
Molecular Role
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Type
Omics
Alteration
Detail
Pathway
Tumor Process
Description
PMID
Type
Omics
Alteration
Detail
Pathway
Tumor Process
Description
PMID
mRNA
Transcriptomics
up-regulation
NA
NA
proliferation
AmpB increased TNF-α expression in microglia and macrophages without the necessity of LPS.
24316889
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Regulation axis
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Regulator Type
Regulator Name
Regulator Effect
Signature
Target Type
Target Name
Target Effect
PMID
Regulator Type
Regulator Name
Regulator Effect
Signature
Target Type
Target Name
Target Effect
PMID
-
-
-
AMPB
protein
TNF-α
activate
24316889
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Experimental Sample
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Disease
Subtype
Grade
Species
Tissue / Cell Line
Description
PMID
Disease
Subtype
Grade
Species
Tissue / Cell Line
Description
PMID
Glioblastoma
pediatric high-grade glioma
G4
Homo Sapiens; Mus musculus
NA
It may be possible to use AmpB to activate monocytoid cells to overcome tumor-induced suppressive microenvironment and curb tumorigenicity.
24316889
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a curated knowledgebase for brain diseases
