BrainBase a curated knowledgebase for brain diseases

Summary

Gene Symbol:	circ-MMP9
Alias:	_
External Link:	GeneCards

Diseases

Drugs

Specific Gene

Brain Specific Gene	Brain-Region Specific Gene	Brain Specific Protein	Cerebrospinal Fluid Protein	Cell Marker

Brain Specific Gene	Brain-Region Specific Gene	Brain Specific Protein	Cerebrospinal Fluid Protein	Cell Marker
-	-	-	-	-

Omics Signature (Glioma)

Molecular Role

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Type	Omics	Alteration	Detail	Pathway	Tumor Process	Description	PMID
circRNA	Transcriptomics	NA	NA	NA	oncogenesis; proliferation; invasion; migration	circMMP9 served as a sponge that directly targeted miR-124.	30470262

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Regulation axis

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Experimental Sample

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Disease	Subtype	Grade	Species	Tissue / Cell Line	Description	PMID
Glioblastoma	NA	G4	Homo sapiens	glioblastoma tissues and corresponding normal tissues	eIF4A3-induced circMMP9 is an important underlying mechanism in GBM cell proliferation, invasion and metastasis through modulation of the miR-124 signaling pathway, which could provide pivotal potential therapeutic targets for the treatment of GBM.	30470262

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