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hsa-mir-124a
Summary
Diseases
Drugs
Specific Gene
Omics Signature
Summary
Gene Symbol:
hsa-mir-124a
Alias:
_
External Link:
GeneCards
Diseases
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Gene Symbol
Disease
Type
PMID
Source
Gene Symbol
Disease
Type
PMID
Source
hsa-mir-124a
Amyotrophic Lateral Sclerosis
miRNA
29670510
HMDD
hsa-mir-124a
Glioma
miRNA
24068568
25175832
29016843
30131250
HMDD
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Drugs
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No data available in table
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Specific Gene
Brain Specific Gene
Brain-Region Specific Gene
Brain Specific Protein
Cerebrospinal Fluid Protein
Cell Marker
Omics Signature (Glioma)
Molecular Role
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Alteration
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Type
Omics
Alteration
Detail
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Tumor Process
Description
PMID
miRNA
Genomics
NA
NA
NA
NA
miR-124a acts by silencing Forkhead box (FOX)A2, an oncogenic transcription factor, resulting in aberrant intracellular lipid accumulation, and that FOXA2 downregulation results in reduced GSC viability.
29016843
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Regulation axis
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PMID
Regulator Type
Regulator Name
Regulator Effect
Signature
Target Type
Target Name
Target Effect
PMID
-
-
-
hsa-mir-124a
NA
FOXA2
inhibit
29016843
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Experimental Sample
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Grade
Species
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Description
PMID
Glioblastoma
NA
G4
Mus musculus
Gli36; U87; U251; LN319; LN229
MSCs can be used as natural biofactories to produce Exo-miR124, which is an effective antiglioma agent worthy of further clinical evaluation.
29016843
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