BrainBase a curated knowledgebase for brain diseases

Diseases:	All Glioblastoma (377) Glioma (244) Medulloblastoma (35)
Omics:	All Genomics (445) Transcriptomics (187) Epigenomics (58) Proteomics (37)
Types:	All mRNA (624) miRNA (21) circRNA (17) lncRNA (5)
Hot genes:	All IDH1 (38) EGFR (27) TP53 (18) MGMT (18) PTEN (14) IDH2 (14) FGFR1 (11) PDGFRA (11) EGFRvIII (10) H3-3A (8) NF1 (7) TERT (7) MET (7) CDKN2A (6) FOXM1 (6) RB1 (5) ACVR1 (5) MYB (5) NOTCH1 (5) OLIG2 (5) EZH2 (5) TGFB1 (5) PIK3CA (4) CD274 (4) PDCD1 (4) NR2E1 (4) VEGFA (4) MYC (4) PROM1 (3) CD44 (3) QKI (3) CDKN2B (3) OTX2 (3) SOX2 (3) hsa-mir-34a (2) circ-MAPK4 (2) TSC2 (2) ACSS2 (2) CCL2 (2) PKM (2) PTCH1 (2) TSC1 (2) PTPN11 (2) RSRC1 (2) SART3 (2) SMAD4 (2) TLR4 (2) SMO (2) SOX10 (2) HAVCR2 (2) STAT3 (2) JAG1 (2) ALKBH5 (2) ATRX (2) BCAN (2) NR1I3 (2) CCND1 (2) CDK4 (2) CIC (2) CTNNB1 (2) CTNND2 (2) FBXW7 (2) FTO (2) FUBP1 (2) KDM6B (2) HNRNPA1 (2) ICOSLG (2) OSMR (2) KMT2C (2) LY6K (2) LZTR1 (2) MBNL1 (2) MBNL2 (2) MBNL3 (2) ELF4 (2) hsa-mir-138 (2) hsa-mir-21 (2) MTORC2 (2) MYCN (2) NOS2 (2) NRL (2) NTRK1 (2)	More

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Disease	Type	Gene Symbol	Omics	Alteration	Pathway	Tumor Process	Potential	PMID
Glioblastoma	mRNA	TNFAIP3	Genomics	NA	NA	NA	Therapy	22585859
Glioblastoma	mRNA	ACSS2	Genomics	wildtype	NA	autophagy	-	28820290
Glioblastoma	mRNA	ACSS2	Genomics	NA	NA	clonogenicity cell death growth viability	Therapy	25525878
Glioblastoma	mRNA	ACVR1	Genomics	mutation	Tyrosine ki-se/RAS/PI3K	NA	-	24705251
Glioblastoma	mRNA	ACVR1	Genomics	mutation	BMP	proliferation	Diagnosis	24705254
Glioblastoma	mRNA	ACVR1	Genomics	mutation	BMP	NA	-	24840074
Glioblastoma	mRNA	ADAM29	Genomics	mutation	NA	NA	Therapy	28854171
Glioblastoma	mRNA	ADSL	Transcriptomics Proteomics	up-regulation	Purine biosynthesis	NA	Prognosis	28346452
Glioblastoma	mRNA	ADSS2	Transcriptomics Proteomics	up-regulation	Purine biosynthesis	NA	Prognosis	28346452
Glioblastoma	mRNA	ALDH1A1	Transcriptomics	up-regulation	NA	proliferation invasion	Prognosis Therapy	29728268

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