基于药物相似性网络数据的药物组合预测方法 提出一种基于图表示学习进行药物组合治疗的预测方法

Manual

Network Embedding framework in Multiplex Networks.  We consider node feature vector should contains all of informaction(ATC,Chemical,side effect....) 

Two applications for NEMN:  DDI prediction.

Data from [33] Gottlieb A, Stein G Y, Oron Y, et al. INDI: a computational framework for inferring drug interactions and their associated recommendations[J]. Molecular Systems Biology, 2012, 8(1): 592. 

Drug combination. Data from DrugBank、SIDER et al. 

Four Steps for NEMN: 

1、evluate network importance 

2、bias random walk for got path 

3、train Skip-gram model 

4、randomforest calssifier 

You can find NEMN in folder of Code. 

Data in Drug combination and Drug-Drug-Interaction.