项目编号 PRJCA000568
项目标题 Transcriptome study of longevity population
涉及领域 Medical
数据类型 Transcriptome or Gene expression
物种名称 Homo sapiens
描述信息 Different from the vast majority of individuals who often suffer from the age-related diseases, longevity people (e.g. centenarians) exhibit unique characteristics of delaying or even escaping many serious age-related diseases (e.g. cardiovascular disease, Alzheimer's disease, type-2 diabetes and cancer). Due to the ability to keep healthy throughout their entire lives, longevity people are excellent subjects for studying the mechanisms of healthy aging. We obtained and analyzed the transcriptomes of peripheral white blood cell of samples (centenarians, their offspring and spouses of offspring) from Chinese longevity families.
样品范围 Monoisolate
发布日期 2023-03-06
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
30352807 Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians Genome Research 10.1101/gr.220780.117 2018
35343058 System-level metabolic modeling facilitates unveiling metabolic signature in exceptional longevity Aging Cell 10.1111/acel.13595 2022
36883688 Enhanced insulin‐regulated phagocytic activities support extreme health span and longevity in multiple populations Aging Cell 10.1111/acel.13810 2023
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
Ministry of Science and Technology of the People's Republic of China (MOST) 2018YFC2000400
提交者 Fu-Hui Xiao (xiaofuhui@mail.kiz.ac.cn)
提交单位 Kunming Institute of Zoology, Chinese Academy of Sciences
提交日期 2017-09-30

项目包含数据信息

资源名称 描述
BioSample (171)  show -
GSA (1) -
CRA000515 RNA-seq of human peripheral white blood cells