| 项目编号 |
PRJCA000763 |
| 项目标题 |
MeCP2 Knockout influence reprogramming |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Raw sequence reads
|
| 物种名称 |
Mus
|
| 描述信息 |
We utilized CRISPR-Cas9 method to obtain MeCP2 knockout mouse. WT and knockout MEF cells were collected from embyro Day-13.5. The influence of MeCP2 on MEF cells were obtained by RNA-Seq method to study reprogramming process. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2018-02-09 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 29562294
|
MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation.
|
Journal of Molecular Cell Biology
|
10.1093/jmcb/mjy018
|
2018
|
|
| 提交者 |
Wei
Zhang (zhangweijing226@126.com)
|
| 提交单位 |
Beijing Institute of Genomics, Chinese Academy of Sciences |
| 提交日期 |
2018-02-09 |