| Accession |
PRJCA000763 |
| Title |
MeCP2 Knockout influence reprogramming |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
|
| Organisms |
Mus
|
| Description |
We utilized CRISPR-Cas9 method to obtain MeCP2 knockout mouse. WT and knockout MEF cells were collected from embyro Day-13.5. The influence of MeCP2 on MEF cells were obtained by RNA-Seq method to study reprogramming process. |
| Sample scope |
Monoisolate |
| Release date |
2018-02-09 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 29562294
|
MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation.
|
Journal of Molecular Cell Biology
|
10.1093/jmcb/mjy018
|
2018
|
|
|
| Submitter |
Wei
Zhang (zhangweijing226@126.com)
|
| Organization |
Beijing Institute of Genomics, Chinese Academy of Sciences |
| Submission date |
2018-02-09 |
