项目编号 PRJCA000763
项目标题 MeCP2 Knockout influence reprogramming
涉及领域 Medical
数据类型 Transcriptome or Gene expression
Raw sequence reads
物种名称 Mus
描述信息 We utilized CRISPR-Cas9 method to obtain MeCP2 knockout mouse. WT and knockout MEF cells were collected from embyro Day-13.5. The influence of MeCP2 on MEF cells were obtained by RNA-Seq method to study reprogramming process.
样品范围 Monoisolate
发布日期 2018-02-09
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
29562294 MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation. Journal of Molecular Cell Biology 10.1093/jmcb/mjy018 2018
提交者 Wei Zhang (zhangweijing226@126.com)
提交单位 Beijing Institute of Genomics, Chinese Academy of Sciences
提交日期 2018-02-09

项目包含数据信息

资源名称 描述
BioSample (4) -
SAMC021033 KOMEF2
SAMC021032 KOMEF1
SAMC021031 WTMEF2
SAMC021030 WTMEF1
GSA (1) -
CRA000764 RNA seq data of Mouse WT MEF cells and MeCP2 Knockout cells