项目编号 PRJCA001124
项目标题 Chinese Prostate Cancer Genome and Epigenome Atlas
涉及领域 Medical
数据类型 Whole genome sequencing
Epigenomics
物种名称 Homo sapiens
描述信息 Chinese Prostate Cancer Genome and Epigenome Atlas, CPGEA, is the largest and most comprehensive cancer genomics study conducted in China. Our genome and epigenome roadmap of prostate cancer for Chinese men is consisted of over 1200 genomic datasets from more than 200 pairs of match normal and primary prostate cancers, providing an invaluable resource and opportunity to complement and compare to previous cancer genomics studies represented by TCGA.
样品范围 Multiisolate
发布日期 2018-11-16
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
32238934 A genomic and epigenomic atlas of prostate cancer in Asian populations Nature 10.1038/s41586-020-2135-x 2020
33414463 KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1 promoter in prostate cancer Cell Death & Disease 10.1038/s41419-020-03354-4 2021
38260432 Systematic analysis of the effects of splicing on the diversity of post-translational modifications in protein isoforms using PTM-POSE bioRxiv 10.1101/2024.01.10.575062 2025
40983631 Induction of ferroptosis in prostate cancer by CCDC719-13 via TRIM21-mediated ubiquitination of SLC7A11 Cell Death and Differentiation 10.1038/s41418-025-01580-x 2025
41036619 Systematic identification of regions where DNA methylation is correlated with transcription refines regulatory logic in normal and tumour tissues Nucleic Acids Research 10.1093/nar/gkaf949 2025
40236781 Profiling chimeric RNA in prostate cancer in Chinese cohorts reveals similarities and differences compared to Western populations iMeta 10.1002/imt2.70014 2025
38932472 An Inherited Allele Confers Prostate Cancer Progression and Drug Resistance via RFX6/HOXA10‐Orchestrated TGFβ Signaling Advanced Science 10.1002/advs.202401492 2024
36841806 NRP1 promotes prostate cancer progression via modulating EGFR-dependent AKT pathway activation Cell Death & Disease 10.1038/s41419-023-05696-1 2023
40576161 Lactylation‐Related Gene LILRB4 Predicts the Prognosis and Immunotherapy of Prostate Cancer Based on Machine Learning Journal of Cellular and Molecular Medicine 10.1111/jcmm.70669 2025
39814752 Causality-driven candidate identification for reliable DNA methylation biomarker discovery Nature Communications 10.1038/s41467-025-56054-y 2025
38978580 Kataegis associated mutational processes linked to adverse prostate cancer presentation in African men Research Square 10.21203/rs.3.rs-4597464/v1 2024
41282084 Single base focal hypermutation cooccurs with structural variation as an early event in advanced prostate tumourigenesis with ancestry specific independence: a multi-ancestral observational study Research Square 10.21203/rs.3.rs-7624142/v1 2025
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
Zhangjiang National Innovation Demonstration Zone Province N/A the "Zhangjiang National Innovation Demonstration Zone" Initiative Development Fund
Ministry of Science and Technology of the People's Republic of China (MOST) 2016YFC0902200 Key Research and Development Project on Precision Medicine
Shanghai 14DZ2272300 the Shanghai Key Laboratory of Cell Engineering
Shanghai 2017ZZ01005 Top Priority Medical Center Project
13th Five-Year Plan 2017ZX093040300002 National Major New Drug Discovery Initiative
National Natural Science Foundation of China (NSFC) 81602467
提交者 Jing Li (ljing@smmu.edu.cn)
提交单位 Second Military Medical University
提交日期 2018-11-16

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