| Accession |
PRJCA001441 |
| Title |
The crosstalk between oocytes and granulosa cells in mouse |
| Relevance |
Model organism |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
|
| Organisms |
Mus musculus
|
| Description |
Follicular development (folliculogenesis) is a well-orchestrated and multistage process including oocyte growth (oogenesis) and maturation, as well as granulosa cell proliferation. The bidirectional communications between oocytes and GCs is vital for oocytes maturation and follicle growth. In this study, we first generated the high-quality mouse transcriptome profiles of oocyte and GCs at seven sequential stages of follicle growth in vivo. Then, we analyzed the key regulators and the significant crosstalk pathways between oocyte and GCs throughout folliculogenesis, which are excepted to be modulated to develop novel approaches to diagnose follicle abnormalities and treat infertility in the future. |
| Sample scope |
Monoisolate |
| Release date |
2021-01-01 |
| Publication |
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2019YFA0110001
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2016YFA0100403
|
|
|
|
| Submitter |
Wenju
Liu (1731481@tongji.edu.cn)
|
| Organization |
Tongji University |
| Submission date |
2019-05-21 |
