项目编号

PRJCA001532

项目标题

Intestinal Microbiome in Children with Autism Spectrum Disorder

涉及领域

Medical

数据类型

Metagenome
Raw sequence reads

物种名称

Bacteria

描述信息

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder, whose incidence is mounting worldwide. There is growing awareness that ASD is highly associated with dysbiosis in gut microbiome. However, the altered pattern of gut microbiome is not consistent across studies and how the microbiome affects ASD is largely unknown. Therefore, we conducted a metagenomic analysis for the intestinal microbiome of 39 ASD children and 40 typical developmental heathy controls (HC) to explore their difference in metabolic functions and microbiome-related pathogenic mechanisms.

样品范围

Environment

发布日期

2020-10-27

出版信息

PubMed ID	文章标题	杂志名称	Doi	发表年份
33087359	A quasi-paired cohort strategy reveals the impaired detoxifying function of microbes in the gut of autistic children	Science Advances	10.1126/sciadv.aba3760	2020
40855005	Probiotics derived sodium benzoate improves social behavior of offspring exposed in the maternal immune activation through regulation of histone lysine benzoylation in astrocytes	Molecular Psychiatry	10.1038/s41380-025-03164-0	2025
39662474	RFW captures species-level metagenomic functions by integrating genome annotation information	Cell Reports Methods	10.1016/j.crmeth.2024.100932	2024

实验材料提供者

Autism research center of Peking University Health Science Center

项目资金来源

机构	项目类型	授权项目ID
National Natural Science Foundation of China (NSFC)	General Program	31671350
Peking University Medical Sciences Center		BJMU88443Y0306
Peking University Medical Sciences Center		BMU2018MX002

提交者

Yanan Chu (chuyn@big.ac.cn)

提交单位

Beijing Institute of Genomics, Chinese Academy of Sciences

提交日期

2019-06-25

项目包含数据信息

资源名称	描述
BioSample (79) show	-
SAMC071936	metagenome seq of TD child faeces FW
SAMC071935	metagenome seq of TD child faeces FV
SAMC071934	metagenome seq of TD child faeces FU
SAMC071933	metagenome seq of TD child faeces FT
SAMC071932	metagenome seq of TD child faeces FR
SAMC071931	metagenome seq of TD child faeces FE
SAMC071930	metagenome seq of TD child faeces FC
SAMC071929	metagenome seq of TD child faeces F78
SAMC071928	metagenome seq of TD child faeces F39M
SAMC071927	metagenome seq of TD child faeces F2HR
SAMC071926	metagenome seq of TD child faeces F29J
SAMC071925	metagenome seq of TD child faeces F28M
SAMC071924	metagenome seq of TD child faeces F28A
SAMC071923	metagenome seq of TD child faeces F1YA
SAMC071922	metagenome seq of TD child faeces F1GY
SAMC071921	metagenome seq of TD child faeces F1GH
SAMC071920	metagenome seq of TD child faeces F1GF
SAMC071919	metagenome seq of TD child faeces F1C3
SAMC071918	metagenome seq of TD child faeces F1C2
SAMC071917	metagenome seq of TD child faeces F1C0
SAMC071916	metagenome seq of TD child faeces F1BV
SAMC071915	metagenome seq of TD child faeces F1BU
SAMC071914	metagenome seq of TD child faeces F1BT
SAMC071913	metagenome seq of TD child faeces F1BP
SAMC071912	metagenome seq of TD child faeces F162
SAMC071911	metagenome seq of TD child faeces F157
SAMC071910	metagenome seq of TD child faeces F156
SAMC071909	metagenome seq of TD child faeces F155
SAMC071908	metagenome seq of TD child faeces F154
SAMC071907	metagenome seq of TD child faeces F153
SAMC071906	metagenome seq of TD child faeces F14A
SAMC071905	metagenome seq of TD child faeces 170711-16
SAMC071904	metagenome seq of TD child faeces 170711-15
SAMC071903	metagenome seq of TD child faeces 170711-14
SAMC071902	metagenome seq of TD child faeces 170711-13
SAMC071901	metagenome seq of TD child faeces 170711-11
SAMC071900	metagenome seq of TD child faeces 170711-10
SAMC071899	metagenome seq of TD child faeces 170629-04
SAMC071898	metagenome seq of TD child faeces 170629-03
SAMC071897	metagenome seq of TD child faeces 170627-01
SAMC071896	metagenome seq of ASD child faeces R079
SAMC071895	metagenome seq of ASD child faeces FP
SAMC071894	metagenome seq of ASD child faeces FD
SAMC071893	metagenome seq of ASD child faeces F79
SAMC071892	metagenome seq of ASD child faeces F63
SAMC071891	metagenome seq of ASD child faeces F62
SAMC071890	metagenome seq of ASD child faeces F61
SAMC071889	metagenome seq of ASD child faeces F6
SAMC071888	metagenome seq of ASD child faeces F2H5
SAMC071887	metagenome seq of ASD child faeces F29D
SAMC071886	metagenome seq of ASD child faeces F28H
SAMC071885	metagenome seq of ASD child faeces F28G
SAMC071884	metagenome seq of ASD child faeces F1GE
SAMC071883	metagenome seq of ASD child faeces F1GD
SAMC071882	metagenome seq of ASD child faeces F1GC
SAMC071881	metagenome seq of ASD child faeces F1GB
SAMC071880	metagenome seq of ASD child faeces F1C1
SAMC071879	metagenome seq of ASD child faeces F17D
SAMC071878	metagenome seq of ASD child faeces F17A
SAMC071877	metagenome seq of ASD child faeces F178
SAMC071876	metagenome seq of ASD child faeces F14V
SAMC071875	metagenome seq of ASD child faeces F10P
SAMC071874	metagenome seq of ASD child faeces F10N
SAMC071873	metagenome seq of ASD child faeces 170920-03
SAMC071872	metagenome seq of ASD child faeces 170920-02
SAMC071871	metagenome seq of ASD child faeces 170911-02
SAMC071870	metagenome seq of ASD child faeces 170901-01
SAMC071869	metagenome seq of ASD child faeces 170831-01
SAMC071868	metagenome seq of ASD child faeces 170818-02
SAMC071867	metagenome seq of ASD child faeces 170811-01
SAMC071866	metagenome seq of ASD child faeces 170727-04
SAMC071865	metagenome seq of ASD child faeces 170724-05
SAMC071864	metagenome seq of ASD child faeces 170724-04
SAMC071863	metagenome seq of ASD child faeces 170711-08
SAMC071862	metagenome seq of ASD child faeces 170711-07
SAMC071861	metagenome seq of ASD child faeces 170711-02
SAMC071860	metagenome seq of ASD child faeces 170629-09
SAMC071859	metagenome seq of ASD child faeces 170629-07
SAMC071858	metagenome seq of ASD child faeces 170629-05
GSA (1)	-
CRA001746	ASD-gut