Accession PRJCA001552
Title Single-heart transcriptome sequencing indicates the gene expression was changed in rnf2-/- heart
Relevance Developmental biology
Data types Transcriptome or Gene expression
Organisms Danio rerio
Description rnf2 is a key component of Polycomb Repressive Complex 1 (PRC1) . The goal of this study is to investigate the function of PRC1 in zebrafish cardiogenesis. The single embryonic hearts were extracted individually from 24 hpf wild type (WT) and rnf2-/- embryos. The mRNA profiles of WT and rnf2-/- hearts were generated by next-generation sequencing, in duplicated. By single-cell transcriptome sequencing, we identified thousands of up- or down-regulated genes in rnf2-/- hearts.
Sample scope Single cell
Release date 2019-07-05
Agency program Grant ID Grant title
Chinese Academy of Sciences (CAS) Y623041501
National Natural Science Foundation of China (NSFC) Y713091501
Ministry of Science and Technology of the People's Republic of China (MOST) 2016YFA0101100
Submitter Xixia    Peng  (
Organization Institute of Hydrobiology, Chinese Academy of Sciences
Submission date 2019-06-27

Project Data

Resource name Description
BioSample (8)  show -
GSA (2) -
CRA002292 rnf2_36h
CRA001761 rnf2 single-heart RNA-seq