项目编号

PRJCA001615

项目标题

Chromatin remodelers-mediated chromatin accessibility facilitates nascent-to-fetal hematopoietic stem and progenitor cell transition

涉及领域

Model organism

数据类型

Epigenomics
Raw sequence reads

物种名称

Danio rerio

描述信息

HSPC development is a dynamic process with different molecular and phenotypical features at different developmental stages. Here, we focused on the dynamic changes in chromatin accessibility and transcriptome features of HSPCs from nascent to fetal states, and uncover the critical role of chromatin remodelers in this process.

样品范围

Multiisolate

发布日期

2020-07-16

出版信息

PubMed ID	文章标题	杂志名称	Doi	发表年份
32756943	Smarca5-mediated epigenetic programming facilitates fetal HSPC development in vertebrates	Blood	10.1182/blood.2020005219	2021
38886858	Reprogramming of 3D genome structure underlying HSPC development in zebrafish	Stem Cell Research & Therapy	10.1186/s13287-024-03798-x	2024

项目资金来源

机构	项目类型	授权项目ID
Chinese Academy of Sciences (CAS)	Strategic Priority Research Program of Chinese Academy of Sciences (CAS)	XDA16010207
Ministry of Science and Technology of the People's Republic of China (MOST)	National Key Technologies R&D Program	2016YFA0100500
National Natural Science Foundation of China (NSFC)		31830061
National Natural Science Foundation of China (NSFC)		31425016
National Natural Science Foundation of China (NSFC)		81530004
Ministry of Science and Technology of the People's Republic of China (MOST)	National Key Technologies R&D Program	2017YFA0102600
Ministry of Science and Technology of the People's Republic of China (MOST)	National Key Technologies R&D Program	2016YFA0100400
Ministry of Science and Technology of the People's Republic of China (MOST)	National Key Technologies R&D Program	2018YFA0800200
Ministry of Science and Technology of the People's Republic of China (MOST)	National Key Technologies R&D Program	2018YFA0801000

提交者

Wen Wang (1510781@tongji.edu.cn)

提交单位

Tongji University

提交日期

2019-07-30

项目包含数据信息

资源名称	描述
BioSample (24) show	-
SAMC086422	ChIP 3dpf Ncl rep2
SAMC086421	ChIP 3dpf Ncl rep1
SAMC086420	ChIP 3dpf Smarca5 rep2
SAMC086419	ChIP 3dpf Smarca5 rep1
SAMC086418	ChIP 3dpf input rep2
SAMC086417	ChIP 3dpf input rep1
SAMC086416	RNA 3dpf mutant rep2
SAMC086415	RNA 3dpf mutant rep1
SAMC086414	RNA 3 dpf sibling rep2
SAMC086413	RNA 3 dpf sibling rep1
SAMC086412	RNA 3 dpf wt rep2
SAMC086411	RNA 3 dpf wt rep1
SAMC086410	RNA 36 hpf wt rep2
SAMC086409	RNA 36 hpf wt rep1
SAMC086408	ATAC 3 dpf mutant rep2
SAMC086407	ATAC 3 dpf mutant rep1
SAMC086406	ATAC 3 dpf siblings rep2
SAMC086405	ATAC 3 dpf siblings rep1
SAMC086404	ATAC 3 dpf wt rep3
SAMC086403	ATAC 3 dpf wt rep2
SAMC086402	ATAC 3 dpf wt rep1
SAMC086401	ATAC 36 hpf wt rep3
SAMC086400	ATAC 36 hpf wt rep2
SAMC086399	ATAC 36 hpf wt rep1
GSA (1)	-
CRA001858	Chromatin remodelers-mediated chromatin accessibility facilitates nascent-to-fetal hematopoietic stem and progenitor cell transition