Accession

PRJCA001868

Title

Single-cell RNA analysis reveals an epithelial-immune dual feature of tumor cells in nasopharyngeal carcinoma

Relevance

Medical

Data types

Whole genome sequencing
Transcriptome or Gene expression

Organisms

Homo sapiens

Description

We performed single-cell RNA-seq on nasopharyngeal biopsies to define the complex interplay between tumor cells, virus infection, and the TME at single-cell resolution. Our results provide new insights into the multicellular ecosystem of NPC and offer important clinical implications.

Sample scope

Single cell

Release date

2022-05-28

Publication

PubMed ID	Article title	Journal name	DOI	Year
32901110	Single-cell transcriptomic analysis defines the interplay between tumor cells, viral infection, and the microenvironment in nasopharyngeal carcinoma	Cell Research	10.1038/s41422-020-00402-8	2020

Biomaterial provider

Sun Yat-sen University Cancer Center

Grants

Agency	program	Grant ID
National Natural Science Foundation of China (NSFC)	General Program	2018ZX10302205
National Natural Science Foundation of China (NSFC)	General Program	31722003
National Natural Science Foundation of China (NSFC)	General Program	81520108022
National Natural Science Foundation of China (NSFC)	General Program	31770925
National Natural Science Foundation of China (NSFC)	General Program	81621004
National Natural Science Foundation of China (NSFC)	General Program	81830090
National Natural Science Foundation of China (NSFC)	General Program	81772883
National Natural Science Foundation of China (NSFC)	General Program	81772895
National Natural Science Foundation of China (NSFC)	General Program	81602371
National Natural Science Foundation of China (NSFC)	General Program	81230045
Guangzhou Sicence Technology and Innovation Commission	General Program	201607020038
National Key Research and development Program		2017YFA0505600
National Key Research and development Program		2016YFC0900102

Submitter

Fan Bai (fbai@pku.edu.cn)

Organization

Peking University

Submission date

2019-10-25

Project Data

Resource name	Description