Accession PRJCA001871
Title The integrated genomic and epigenomic landscape of brainstem glioma
Relevance Medical
Data types Whole genome sequencing
Epigenomics
Exome
Targeted Locus (Loci)
Transcriptome or Gene expression
Raw sequence reads
Organisms
Description Brainstem gliomas are a heterogeneous group of tumors that encompass both benign tumors cured with surgical resection and highly lethal cancers with no efficacious therapies. We performed a comprehensive study incorporating epigenetic and genomic analyses on a large cohort of brainstem gliomas, including Diffuse Intrinsic Pontine Gliomas. Our findings indicate that the integration of genetic and epigenetic data can facilitate a better understanding of brainstem gliomagenesis and classification, and guide future studies for the development of novel treatments for this disease.
Sample scope Multiisolate
Release date 2020-03-05
Grants
Agency program Grant ID Grant title
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2014BAI04B01 Neurosurgery research for brain tumor
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2015BAI12B04
National Natural Science Foundation of China (NSFC) General Program 81872048
Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support ZYLX201608
Beijing Municipal Science and Technology Comission Beijing Municipal Natural Science Foundation 7161004
Submitter Liwei    Zhang  (panchangcun@bjtth.org)
Organization Beijing Tiantan Hospital Capital Medical University
Submission date 2019-10-28

Project Data

Resource name Description