Accession | PRJCA001871 | ||||||||||||||||||||||||
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Title | The integrated genomic and epigenomic landscape of brainstem glioma | ||||||||||||||||||||||||
Relevance | Medical | ||||||||||||||||||||||||
Data types |
Whole genome sequencing
Epigenomics Exome Targeted Locus (Loci) Transcriptome or Gene expression Raw sequence reads |
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Organisms | |||||||||||||||||||||||||
Description | Brainstem gliomas are a heterogeneous group of tumors that encompass both benign tumors cured with surgical resection and highly lethal cancers with no efficacious therapies. We performed a comprehensive study incorporating epigenetic and genomic analyses on a large cohort of brainstem gliomas, including Diffuse Intrinsic Pontine Gliomas. Our findings indicate that the integration of genetic and epigenetic data can facilitate a better understanding of brainstem gliomagenesis and classification, and guide future studies for the development of novel treatments for this disease. | ||||||||||||||||||||||||
Sample scope | Multiisolate | ||||||||||||||||||||||||
Release date | 2020-03-05 | ||||||||||||||||||||||||
Grants |
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Submitter | Liwei Zhang (panchangcun@bjtth.org) | ||||||||||||||||||||||||
Organization | Beijing Tiantan Hospital Capital Medical University | ||||||||||||||||||||||||
Submission date | 2019-10-28 |
Resource name | Description |
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