| Accession |
PRJCA002131 |
| Title |
Prefrontal cortex regulatory profiling on the East Asian population |
| Relevance |
Medical |
| Data types |
Whole genome sequencing
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
To identify genetic variants regulating brain gene expression and alternative splicing in the East Asian population, we performed high-density genotyping and high throughput RNA sequencing in 151 prefrontal cortex brain tissue. After quality control and preprocessing the genotype and RNA-seq data, we obtained a set of 18,939 brain expressed genes and 6.4 million autosomal single nucleotide polymorphisms (SNPs) from each individual. Then we performed eQTL and sQTL mapping as well as co-regulatory network construction to compile the first genome-wide brain prefrontal cortex regulatory map on the East Asian population. |
| Sample scope |
Multiisolate |
| Release date |
2021-01-01 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
31571312
|
National Natural Science Foundation of China
|
|
|
| Submitter |
Chao
Chen (chenchao@sklmg.edu.cn)
|
| Organization |
Central South University |
| Submission date |
2020-01-06 |
