| Accession |
PRJCA002513 |
| Title |
Genomic variations of multi-grade esophageal squamous dysplasia |
| Relevance |
Medical |
| Data types |
Whole genome sequencing
Exome
Raw sequence reads
|
| Organisms |
Homo sapiens
|
| Description |
The majority of esophageal squamous dysplasia (ESD) are growing slowly, while a subset can undergo recurrence rapidly and progress with lethal consequences even after proper treatment. In the present study, we performed whole-exome sequencing on 105 clinical samples from 80 tumor-free ESD patients. Those genomic variations largely expanded our understanding in genetics and biology of ESD, which possessed promising significance for improving early diagnosis, reducing overtreatment, and identifying high risk ESD patients. |
| Sample scope |
Multispecies |
| Release date |
2020-04-10 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
81830086
|
|
| National Natural Science Foundation of China (NSFC)
|
|
81988101
|
|
| Beijing Municipal Commission of Health and Family Planning Project
|
|
PXM2018026279000005
|
|
|
|
| Submitter |
Qimin
Zhan (zhanqimin@bjmu.edu.cn)
|
| Organization |
Peking University Cancer Hospital & Institute |
| Submission date |
2020-04-10 |
