| 项目编号 | PRJCA002573 | |||||||||||||||
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| 项目标题 | Global Characterization of CD45+ Immune Cells States in Peripheral Blood and Synovial Tissues of ACPA-negative and ACPA-positive Rheumatoid Arthritis Patients by Single-cell Sequencing | |||||||||||||||
| 涉及领域 | autoimmunity disease | |||||||||||||||
| 数据类型 | Transcriptome or Gene expression | |||||||||||||||
| 物种名称 | Homo sapiens | |||||||||||||||
| 描述信息 | The immune pathogenesis mechanisms that underlie ACPA-positive and ACPA-negative RA are not well understood. Here, we profiled 100,551 cells from peripheral blood and synovial tissue of seven ACPA-positive and seven ACPA-negative RA patients as well as healthy controls by single-cell RNA sequencing, which enabled identification and characterization of specific subsets of immune cells related to RA pathogenesis. | |||||||||||||||
| 样品范围 | Single cell | |||||||||||||||
| 发布日期 | 2020-12-31 | |||||||||||||||
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| 提交者 | Xuan Zhang (zxpumch2003@sina.com) | |||||||||||||||
| 提交单位 | Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College | |||||||||||||||
| 提交日期 | 2020-04-22 |
| 资源名称 | 描述 |
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| BioSample (60) show | - |