Accession PRJCA002589
Title Single-cell transcriptomic atlas of primate cardiopulmonary aging
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Macaca fascicularis
Description This project created young and old non-human primate (NHP) single-nucleus/cell transcriptomic atlases of lung, heart, and artery, known as the top tissues targeted by SARS-CoV-2. The aim of this project is to reveal cell type-specific aging-related transcriptional changes of cardiopulmonary tissues and the underlying mechanism of age-linked susceptibility to SARS-CoV-2.
Sample scope Single cell
Release date 2020-09-06
Publication
PubMed ID Article title Journal name DOI Year
32913304 Single-cell transcriptomic atlas of primate cardiopulmonary aging Cell Research 10.1038/s41422-020-00412-6 2021
Grants
Agency program Grant ID Grant title
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2017YFA0103300
Submitter Shuai    Ma  (mashuai3ban@126.com)
Organization Institute of Zoology, Chinese Academy of Sciences
Submission date 2020-04-24

Project Data

Resource name Description
BioSample (21)  show -
GSA (2) -
CRA002577 Single-nucleus RNA-seq of lungs from young and aged cynomolgus monkeys
CRA002689 Single-nucleus RNA-seq of hearts from young and aged cynomolgus monkeys