Accession PRJCA002625
Title CRISPR/Cas9-mediated whole genomic wide knockout screening identifies mitochondrial ribosomal proteins involving in OGDR resistance
Relevance Medical
Data types Raw sequence reads
Organisms Homo sapiens
Description Therefore, in this study, we subjected SK-N-BE(2) cells to oxygen-glucose deprivation/reperfusion(OGDR) insult and performed a pooled genome-wide CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) knockout screen to discover new potential therapeutic targets for cerebral ischemia-reperfusion injury.
Sample scope PCR product deep sequencing
Release date 2020-05-03
Publication
PubMed ID Article title Journal name DOI Year
32618081 CRISPR/Cas9-mediated whole genomic wide knockout screening identifies mitochondrial ribosomal proteins involving in oxygen-glucose deprivation/reperfusion resistance Journal of Cellular and Molecular Medicine 10.1111/jcmm.15580 2020
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) General Program 81771423
National Natural Science Foundation of China (NSFC) General Program 81974212
Submitter Jieqiong    Tan  (tanjieqiong@sklmg.edu.cn)
Organization Central South University
Submission date 2020-05-03

Project Data

Resource name Description
BioSample (1) -
SAMC185151 SKN2 OGDR
GSA (1) -
CRA002630 SKN2 OGDR