项目编号 PRJCA002800
项目标题 Evolution under spatially-heterogeneous selection in solid tumors
涉及领域 Evolution
数据类型 Whole genome sequencing
Raw sequence reads
物种名称 Homo sapiens
描述信息 Multi-stage tumorigenesis and clonal evolution model described previously indicate that solid tumor is temporally and spatially heterogeneous, samples collected at different time points or spatial positions providing various genetic information. Based on this, we performed three-dimensional micro-dissection and whole-genome sequencing (WGS) for two tumors at a relatively early stage to comprehensively trace the mutation evolutionary process of tumors and decipher their clonal distribution in three dimensions.
样品范围 Multiisolate
发布日期 2022-01-13
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
34850073 Evolution under Spatially Heterogeneous Selection in Solid Tumors Molecular Biology and Evolution 10.1093/molbev/msab335 2022
36894662 State-dependent evolutionary models reveal modes of solid tumour growth Nature Ecology & Evolution 10.1038/s41559-023-02000-4 2023
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) 9153130008
提交者 Xuemei Lu (xuemeilu@mail.kiz.ac.cn)
提交单位 Kunming Institute of Zoology, Chinese Academy of Sciences
提交日期 2020-06-05

项目包含数据信息

资源名称 描述
BioSample (330)  show -