| Accession | PRJCA002823 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Title | lncRNAs in leukemia glucocorticoid resistance | ||||||||
| Relevance | Medical | ||||||||
| Data types |
Epigenomics
Transcriptome or Gene expression Genome sequencing |
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| Organisms | Homo sapiens | ||||||||
| Description | Resistance to glucocorticoid is a major obstacle to effective treatment ,but the mechanism has not been studied very clearly. This study GC-sensitive AML used GC-sensitive AML cell line Kasumi-1 and established GC-resistant cell strain through GC treatment in vitro. Based on these sensitive-resistant cell pairs we found HOTAIRM1 was highly expressed in resistant cells, and its high expression contributed to GC resistance. | ||||||||
| Sample scope | Monoisolate | ||||||||
| Release date | 2020-06-09 | ||||||||
| Grants |
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| Submitter | liang liang (liangl@big.ac.cn) | ||||||||
| Organization | ucas | ||||||||
| Submission date | 2020-05-11 |