| Accession |
PRJCA003026 |
| Title |
Identification of globin switching-related genes and RNAs via transcriptomic profiling of nucleated red blood cells isolated from the cord blood of preterm and full-term newborns |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
In this study, we compared the transcriptome profiles of nucleated red blood cells freshly isolated from preterm and full-term neonate cord blood, with the aim of identifying genes related to globin switching. We confirmed the differential expression of genes and RNAs with known associations with globin switching in preterm and full-term samples, and discovered novel associations of transcripts, genes, and pathways with globin switching. We believe that our study makes a significant contribution to the literature because it utilizes freshly isolated ex vivo samples rather than cultured cells for analysis, thereby more faithfully reporting physiological expression levels. |
| Sample scope |
Multiisolate |
| Release date |
2020-09-11 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
81660023/81960040
|
|
|
|
| Submitter |
shengwen
Huang (hsw713@sina.com)
|
| Organization |
Guizhou Provincial People's Hospital |
| Submission date |
2020-07-11 |
