项目编号 PRJCA003192
项目标题 Gene knocked out in Mycobacterium tuberculosis
涉及领域 Medical
先导项目

eGPS: evolutionary Genotype-Phenotype Systems biology

Key theories & Model

Special portal and non model biological system

数据类型 Whole genome sequencing
物种名称 Mycobacterium tuberculosis
描述信息 We repurposed an endogenous type III-A CRISPR-Cas to enable programmable genome editing and RNA level knockdown in Mycobacterium tuberculosis (Mtb). The latter CRISPRi tool was also successfully applied to screen out growth-regulation genes for this important human pathogen
样品范围 Lab cultured
发布日期 2020-08-07
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
34923124 Reprogramming Mycobacterium tuberculosis CRISPR System for Gene Editing and Genome-wide RNA Interference Screening Genomics, Proteomics & Bioinformatics 10.1016/j.gpb.2021.01.008 2021
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) Major Research Plan C180501 Vaccine searching for TB
Chinese Academy of Sciences (CAS) Strategic Priority Research Program of Chinese Academy of Sciences (CAS) XDB13000000
提交者 khaista rahman (3027224182@qq.com)
提交单位 Huazhong Agricultural University
提交日期 2020-08-05

项目包含数据信息

资源名称 描述
BioSample (4) -
SAMC204698 M_KO3
SAMC204697 M_KO2
SAMC204689 M_KO1
SAMC204687 M_Ctrl1
GSA (1) -
CRA003057 Gene knocked out in Mycobacterium tuberculosis