| Accession |
PRJCA003273 |
| Title |
Effects of Ochratoxin A exposure on DNA damage in porcine granulosa cells in vitro |
| Relevance |
Environmental |
| Data types |
Raw sequence reads
|
| Organisms |
Sus scrofa
|
| Description |
Ochratoxin A (OTA), a feed mycotoxin, tends to impair the reproductive health of animals. Our previous studies have demonstrated that OTA is harmful to porcine granulosa cells (GCs) growth and induces GCs apoptosis, but the inner toxic mechanism is still uncertain. In this study, we explored the toxic mechanism of OTA exposure on porcine GCs in vitro, we found that OTA exposure inhibits the proliferation of porcine GCs and arrested cell cycle of GCs in the G2/M phase. |
| Sample scope |
granulosa cell |
| Release date |
2020-08-20 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
|
|
Effects of Ochratoxin A exposure on DNA damage in porcine granulosa cells in vitro
|
Toxicology Letters
|
10.1016/j.toxlet.2020.05.011
|
2020
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Taishan Scholar Construction Foundation of Shandong Province
|
|
ts20190946
|
|
|
|
| Submitter |
Kong
Li (17854231149@163.com)
|
| Organization |
Qing dao agriculture university |
| Submission date |
2020-08-18 |
