| 项目编号 |
PRJCA003568 |
| 项目标题 |
The relationship between lower respiratory tract microbiome and allergic respiratory tract diseases in children |
| 涉及领域 |
Medical |
| 数据类型 |
Metagenome
|
| 物种名称 |
Bacteria
|
| 描述信息 |
With the development of sequencing technologies, it has been found that there are microbes similar with the upper respiratory tract in the healthy human low respiratory tract, including lungs and bronchus. For the study of children's lower respiratory microbiome and the relationship between allergic respiratory diseases, we choose 68 children, who were in the respiratory department of hospital affiliated to the capital institute of pediatrics and processed bronchoscope. Using the total IgE (TIgE) values, children can be divided into two groups, one group of 34 cases of allergy (allergy sensitivity, AS), 34 cases of no allergy (no allergy sensitivity, NAS). Nucleic acid was extracted from the samples of bronchoalveolar lavage fluid (BALF) taken by bronchoscopy treatment, and then 16S rRNA gene was sequenced and analyzed. |
| 样品范围 |
Environment |
| 发布日期 |
2021-05-13 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 34054744
|
The Relationship Between Lower Respiratory Tract Microbiome and Allergic Respiratory Tract Diseases in Children
|
Frontiers in Microbiology
|
10.3389/fmicb.2021.630345
|
2021
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Public service development and reform pilot project of Beijing Medical Research Institute
|
|
BMR201911
|
|
|
|
| 提交者 |
Jiarui
Li (li.jiarui@ccmu.edu.cn)
|
| 提交单位 |
Beijing Ditan Hospital, Capital Medical University |
| 提交日期 |
2020-09-29 |
