| 项目编号 |
PRJCA003616 |
| 项目标题 |
Heterogeneity and clonal relationships of T cells in TPE revealed by single-cell immune profiling |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Coupled scRNA-seq and scTCR-seq were performed on paired peripheral blood mononuclear cell (PBMCs) and pleural fluid mononuclear cell (PFMCs) samples from four TPE patients to evaluate the T-cell composition and function at the site of Mtb infection. |
| 样品范围 |
Single cell |
| 发布日期 |
2020-10-09 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 41278845
|
The tuberculosis-associated microenvironment promotes HIV-1 persistence by impairing CD8+ T cell-mediated viral control
|
bioRxiv
|
10.1101/2025.10.14.682453
|
2025
|
| 40607390
|
Single-cell analysis of peripheral blood and pleural effusion reveals functional diversity of γδ T cells in tuberculosis infection
|
Frontiers in Immunology
|
10.3389/fimmu.2025.1605827
|
2025
|
| 39886461
|
Hyperglycemic milieu impairs Vγ9Vδ2 T cell functions in tuberculosis patients and prolongs M.tb negative conversion time
|
iScience
|
10.1016/j.isci.2024.111692
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
81871255
|
|
| National Natural Science Foundation of China (NSFC)
|
|
91942315
|
|
|
|
| 提交者 |
Yi
Cai (caiyi0113@szu.edu.cn)
|
| 提交单位 |
Shenzhen University |
| 提交日期 |
2020-10-09 |
