Accession PRJCA003708
Title RNA-seq of tissue and blood samples from thoracic aortic aneurysm and dissection
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Homo sapiens
Description Thoracic aortic tissue was obtained from 8 TAAD human patients undergoing thoracic aneurysm repair surgery. As a control, thoracic aortic tissue from 6 donors with cardiomyopathy undergoing cardiac transplantation was also collected. These tissue samples were subjected to bulk RNA-seq. In addition, to examine the transcriptomic characteristics of macrophages/monocytes in TAAD patients, thoracic aortic tissue and peripheral blood from four TAAD patients were collected. CD11b+ macrophages/monocytes were sorted with antibody-bound magnetic beads from tissue and PBMCs. CD11b+ cells of tissue, CD11b- cells of tissue and CD11b+ PBMCs were subjected to bulk RNA-seq.
Sample scope Multiisolate
Release date 2020-10-21
Grants
Agency program Grant ID Grant title
No funding support
Submitter Zhou    Zhou  (zhouzhoufuwai@126.com)
Organization Fuwai Hospital, Chinese Academy of Medical Sciences
Submission date 2020-10-21

Project Data

Resource name Description
BioSample (26)  show -