Accession |
PRJCA003708 |
Title |
RNA-seq of tissue and blood samples from thoracic aortic aneurysm and dissection |
Relevance |
Medical |
Data types |
Transcriptome or Gene expression
|
Organisms |
Homo sapiens
|
Description |
Thoracic aortic tissue was obtained from 8 TAAD human patients undergoing thoracic aneurysm repair surgery. As a control, thoracic aortic tissue from 6 donors with cardiomyopathy undergoing cardiac transplantation was also collected. These tissue samples were subjected to bulk RNA-seq. In addition, to examine the transcriptomic characteristics of macrophages/monocytes in TAAD patients, thoracic aortic tissue and peripheral blood from four TAAD patients were collected. CD11b+ macrophages/monocytes were sorted with antibody-bound magnetic beads from tissue and PBMCs. CD11b+ cells of tissue, CD11b- cells of tissue and CD11b+ PBMCs were subjected to bulk RNA-seq. |
Sample scope |
Multiisolate |
Release date |
2020-10-21 |
Grants |
Agency |
program |
Grant ID |
Grant title |
No funding support
|
|
|
|
|
Submitter |
Zhou
Zhou (zhouzhoufuwai@126.com)
|
Organization |
Fuwai Hospital, Chinese Academy of Medical Sciences |
Submission date |
2020-10-21 |