Accession

PRJCA003819

Title

The Whole-exome sequencing of alpha-fetoprotein producing gastric carcinoma (AFPGC) reveals genomic profile and therapeutic targets

Relevance

Medical

Data types

Exome
Genome sequencing

Organisms

Homo sapiens

Description

Alpha-fetoprotein producing gastric carcinoma (AFPGC) is a rare and aggressive subtype of gastric cancer. We collected 58 AFPGC patients for whole-exome sequencing in order to revealing genomic profile and therapeutic targets.

Sample scope

Multiisolate

Release date

2020-11-02

Publication

PubMed ID	Article title	Journal name	DOI	Year
34168152	Whole-exome sequencing of alpha-fetoprotein producing gastric carcinoma reveals genomic profile and therapeutic targets	Nature Communications	10.1038/s41467-021-24170-0	2021

Grants

Agency	program	Grant ID	Grant title
National Natural Science Foundation of China (NSFC)		81803107
Zhejiang Provincial Natural Science Foundation of China		LQ18H160002
Key Research and Development Program of Science and Technology Department of Zhejiang Province		2018C03022
Zhejiang Provincial Department of Science and Technology		2020C03112
Project of the regional diagnosis and treatment centre of the Health Planning Committee		JBZX-201903

Submitter

Jun Lu (1315017@zju.edu.cn)

Organization

The First Affiliated Hospital, Zhejiang University School of Medicine

Submission date

2020-11-02

Project Data

Resource name	Description
BioSample (116) show	-
SAMC1536012	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 58
SAMC1536007	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 58
SAMC1536003	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 57
SAMC1536000	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 57
SAMC1535995	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 56
SAMC1535990	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 56
SAMC1535986	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 55
SAMC1535981	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 55
SAMC1535979	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 54
SAMC1535975	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 54
SAMC1535971	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 53
SAMC1535966	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 53
SAMC1535962	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 52
SAMC1535960	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 52
SAMC1535957	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 51
SAMC1535954	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 51
SAMC1535951	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 50
SAMC1535946	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 50
SAMC1535943	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 49
SAMC1535939	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 49
SAMC1535935	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 48
SAMC1535932	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 48
SAMC1535927	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 47
SAMC1535923	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 47
SAMC1535921	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 46
SAMC1535917	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 46
SAMC1535912	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 45
SAMC1535908	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 45
SAMC1535903	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 44
SAMC1535900	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 44
SAMC1535895	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 43
SAMC1535892	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 43
SAMC1535889	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 42
SAMC1535886	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 42
SAMC1535883	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 41
SAMC1535879	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 41
SAMC1535875	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 40
SAMC1535873	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 40
SAMC1535869	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 39
SAMC1535865	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 39
SAMC1535861	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 38
SAMC1535857	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 38
SAMC1535852	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 37
SAMC1535847	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 37
SAMC1535844	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 36
SAMC1535841	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 36
SAMC1535838	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 35
SAMC1535834	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 35
SAMC1535830	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 34
SAMC1535826	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 34
SAMC1535823	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 33
SAMC1535818	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 33
SAMC1535814	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 32
SAMC1535811	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 32
SAMC1535806	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 31
SAMC1535802	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 31
SAMC1535799	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 30
SAMC1535795	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 30
SAMC1535791	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 29
SAMC1535787	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 29
SAMC1535783	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 28
SAMC1535779	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 28
SAMC1535776	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 27
SAMC1535773	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 27
SAMC1535769	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 26
SAMC1535765	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 26
SAMC1535762	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 25
SAMC1535757	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 25
SAMC1535754	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 24
SAMC1535748	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 24
SAMC1535744	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 23
SAMC1535740	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 23
SAMC1535736	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 22
SAMC1535732	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 22
SAMC1535729	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 21
SAMC1535725	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 21
SAMC1535721	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 20
SAMC1535717	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 20
SAMC1535714	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 19
SAMC1535709	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 19
SAMC1535705	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 18
SAMC1535701	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 18
SAMC1535696	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 17
SAMC1535693	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 17
SAMC1535689	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 16
SAMC1535686	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 16
SAMC1535684	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 15
SAMC1535679	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 15
SAMC1535675	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 14
SAMC1535672	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 14
SAMC1535668	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 13
SAMC1535664	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 13
SAMC1535660	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 12
SAMC1535655	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 12
SAMC1535651	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 11
SAMC1535648	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 11
SAMC1535644	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 10
SAMC1535640	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 10
SAMC1535636	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 09
SAMC1535632	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 09
SAMC1535628	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 08
SAMC1535624	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 08
SAMC1535620	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 07
SAMC1535617	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 07
SAMC1535614	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 06
SAMC1535609	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 06
SAMC1535606	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 05
SAMC1535601	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 05
SAMC1535597	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 04
SAMC1535594	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 04
SAMC1535590	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 03
SAMC1535588	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 03
SAMC1535584	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 02
SAMC1535582	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 02
SAMC1535578	fresh-frozen and/or FFPE tumor tissues of AFPGC patient number 01
SAMC1535575	fresh-frozen and/or FFPE matched tumor adjacent normal tissues of AFPGC patient number 01