| 项目编号 |
PRJCA004071 |
| 项目标题 |
Heterophil/lymphocyte selected population study reveals PTPRJ associates immune defense of Heterophils in chicken |
| 涉及领域 |
Agricultural |
| 数据类型 |
Whole genome sequencing
Raw sequence reads
|
| 物种名称 |
Gallus
|
| 描述信息 |
In this study, we compared chicken populations with differing H/L ratios in terms of mortality after ST infection and heterophil function. Using a H/L directional selection line, we evaluated selection progress at both phenotypic and genomic levels, and further located genes relating to H/L based on the selection signal, GWAS, and transcriptome data. Our purpose is to explore the mechanism by which SNPs affect differences in Salmonella resistance. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2022-12-18 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 36807561
|
A heterophil/lymphocyte-selected population reveals the phosphatase PTPRJ is associated with immune defense in chickens
|
Communications Biology
|
10.1038/s42003-023-04559-x
|
2023
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
32072708
|
|
| National Key R&D Program of China
|
|
2018YFE0128000
|
|
| Major scientific research projects of Chinese Academy of Agricultural Sciences
|
|
CAAS-ZDRW202005
|
|
|
|
| 提交者 |
jie
wang (wangjie4007@126.com)
|
| 提交单位 |
CAAS |
| 提交日期 |
2020-12-17 |
