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Accession PRJCA004090
Title Single-cell Transcriptomic Landscape of Human Blood Cells
Relevance Medical
Data types Transcriptome or Gene expression
Raw sequence reads
Organisms
Description We profiled the transcriptomes of 7,643 human blood cells covering 32 immunophenotypic cell types across 21 healthy donors. We constructed the single-cell transcriptional atlas of blood cells on the basis of protein-coding genes and long noncoding RNAs (lncRNAs) respectively, and showed a high consistence between them. Notably, lncRNAs and novel transcription factors regulating hematopoietic cell differentiation were identified.
Sample scope Single cell
Release date 2020-12-31
Publication
PubMed ID Article title Journal name DOI Year
Single-cell Transcriptomic Landscape of Human Blood Cells National Science Review doi.org/10.1093/nsr/nwaa180
Grants
Agency program Grant ID Grant title
Ministry of Science and Technology of the People's Republic of China (MOST) 2018YFA0107801
Ministry of Science and Technology of the People's Republic of China (MOST) 2016YFA0100600
Ministry of Science and Technology of the People's Republic of China (MOST) 2017YFA0103400
National Key Research and Development Program of China 2018YFA0107804
National Natural Science Foundation of China (NSFC) 81670106
National Natural Science Foundation of China (NSFC) 81421002
National Natural Science Foundation of China (NSFC) 81730006
National Natural Science Foundation of China (NSFC) 81890990
National Natural Science Foundation of China (NSFC) 81970104
National Natural Science Foundation of China (NSFC) 32000803
CAMS Initiative for Innovative Medicine 2017-I2M-1-015
CAMS Initiative for Innovative Medicine 2019-I2M-1-006
CAMS Initiative for Innovative Medicine 2016-I2M-1-017
CAMS Initiative for Innovative Medicine 2019-I2M-2-001
External link
External link Link description
http://scrna.sklehabc.com/ Atlas of Human Blood Cells
Submitter Xiaowei    Xie  (xiexiaowei@ihcams.ac.cn)
Organization Institute of Hematology and Blood Diseases Hospital
Submission date 2020-12-21

Project Data

Resource name Description