| Accession |
PRJCA004279 |
| Title |
m6A modifications are widespread in EBV transcripts in NPC cells and primary cancer cells |
| Relevance |
Medical |
| Data types |
Raw sequence reads
|
| Organisms |
Homo sapiens
|
| Description |
To determine the presence of potential m6A modification sites in the EBV epitranscriptome, we performed methylated RNA immunoprecipitation and sequencing (MeRIP-seq) on various cells infected with EBV in different life cycle and different biopsies. The examined samples included NPEC1-Bmi1 cells and HK1 cells with acute EBV infection, C666 cells and CNE2EBV cells with latent EBV infection, CNE2EBV cells with lytic EBV reactivation, B cells with latent infection or lytic reactivation, one non-tumor nasopharyngeal biopsy, two primary NPC biopsies, and two NPC patient-derived xenograft (PDX) tissues. |
| Sample scope |
Multiisolate |
| Release date |
2021-01-16 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 33605073
|
N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay
|
EMBO Reports
|
10.15252/embr.202050128
|
2021
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
81830090
|
|
|
|
| Submitter |
Musheng
Zeng (zengmsh@sysucc.org.cn)
|
| Organization |
Sun Yat-sen University Cancer Center |
| Submission date |
2021-01-16 |
