Accession

PRJCA004455

Title

A spatiotemporal single-cell atlas of cis-regulatory elements in mouse embryos

Relevance

Medical

Data types

Epigenomics
Transcriptome or Gene expression

Organisms

Mus musculus
Mus

Description

Here, we report a single-cell resolution comprehensive map of chromatin accessibility together with gene expression for 3 embryonic germ layers (at E7.5) and all representative fetal organs (from E11.5, E12.5 and E13.5) of the mouse embryos. In total, we performed paired scRNA-seq and scATAC-seq to profile more than 500,000 single cells.

Sample scope

Single cell

Release date

2023-02-18

Publication

PubMed ID	Article title	Journal name	DOI	Year
36881507	Single-cell chromatin accessibility and transcriptome atlas of mouse embryos	Cell Reports	10.1016/j.celrep.2023.112210	2023

Grants

Agency	program	Grant ID	Grant title
Ministry of Science and Technology of the People's Republic of China (MOST)	National Key Technologies R&D Program	2019YFA0801700	Molecular Mechanisms of Metabolic and Epigenetic Modification Interactions in Regulating Cell Fate Decisions
Chinese Academy of Sciences (CAS)	Strategic Priority Research Program of Chinese Academy of Sciences (CAS)	XDB38020500

Submitter

JiangLab BIG (jianglab-gsa@big.ac.cn)

Organization

Beijing Institute of Genomics, Chinese Academy of Sciences

Submission date

2021-02-04

Project Data

Resource name	Description
BioSample (22) show	-
SAMC338313	paired scRNA-seq and scATAC-seq of Mus musculus: Gonad-female_E11.5
SAMC338312	paired scRNA-seq and scATAC-seq of Mus musculus: Gonad-male_E11.5
SAMC338311	paired scRNA-seq and scATAC-seq of Mus musculus: GermLayer_E7.5
SAMC338310	paired scRNA-seq and scATAC-seq of Mus musculus: Eye_E13.5
SAMC338309	paired scRNA-seq and scATAC-seq of Mus musculus: Heart_E13.5
SAMC338308	paired scRNA-seq and scATAC-seq of Mus musculus: Gonad-female_E12.5
SAMC338307	paired scRNA-seq and scATAC-seq of Mus musculus: Gonad-male_E12.5
SAMC338306	paired scRNA-seq and scATAC-seq of Mus musculus: ForeLimb_E13.5
SAMC338305	paired scRNA-seq and scATAC-seq of Mus musculus: Gonad-female_E13.5
SAMC338304	paired scRNA-seq and scATAC-seq of Mus musculus: Gonad-male_E13.5
SAMC338303	paired scRNA-seq and scATAC-seq of Mus musculus: Kidney_E13.5
SAMC338302	paired scRNA-seq and scATAC-seq of Mus musculus: Intestine_E13.5
SAMC338301	paired scRNA-seq and scATAC-seq of Mus musculus: Stomach_E13.5
SAMC338300	paired scRNA-seq and scATAC-seq of Mus musculus: Lung_E13.5
SAMC338299	paired scRNA-seq and scATAC-seq of Mus musculus: SpinalCord_E13.5
SAMC338298	paired scRNA-seq and scATAC-seq of Mus musculus: Brain-hind_E13.5
SAMC338297	paired scRNA-seq and scATAC-seq of Mus musculus: Brain-mid_E13.5
SAMC338296	paired scRNA-seq and scATAC-seq of Mus musculus: Brain-fore_E13.5
SAMC338295	paired scRNA-seq and scATAC-seq of Mus musculus: Spleen_E13.5
SAMC338294	paired scRNA-seq and scATAC-seq of Mus musculus: Pancreas_E13.5
SAMC338293	paired scRNA-seq and scATAC-seq of Mus musculus: Liver_E13.5
SAMC338292	paired scRNA-seq and scATAC-seq of Mus musculus: Lung_E12.5
GSA (1)	-
CRA003910	Single-cell chromatin accessibility and transcriptome atlas of mouse embryos