Accession |
PRJCA004500 |
Title |
MeRIP-seq in EBV infected HK1 and NP460 cells |
Relevance |
Medical |
Data types |
Raw sequence reads
|
Organisms |
Homo sapiens
|
Description |
To identify the m6A modification changes in cellular mRNAs following EBV infection, we performed methylated RNA immunoprecipitation and sequencing (MeRIP-seq) of infected versus uninfected nasopharyngeal epithelial cells (Fig. 1A). After extracting the mRNA from NP460 and HK1 cells at 24h post-infected with EBV, we used an anti-m6A antibody to enrich m6A-modified RNA fragments prior to RNA sequencing of both the input and immunoprecipitated fractions for MeRIP-seq. |
Sample scope |
Monoisolate |
Release date |
2021-02-18 |
Publication |
PubMed ID |
Article title |
Journal name |
DOI |
Year |
33741341
|
Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein-Barr virus infection
|
The Journal of Biological Chemistry
|
10.1016/j.jbc.2021.100547
|
2021
|
|
Grants |
Agency |
program |
Grant ID |
Grant title |
National Natural Science Foundation of China (NSFC)
|
|
81830090
|
|
|
Submitter |
Musheng
Zeng (zengmsh@sysucc.org.cn)
|
Organization |
Sun Yat-sen University Cancer Center |
Submission date |
2021-02-18 |