Accession PRJCA004622
Title Whole exome sequencing of patients with CRC from the Changkang project
Relevance Medical
Data types Exome
Raw sequence reads
Organisms Homo sapiens
Description Colorectal cancer (CRC) is a heterogeneous disease with high varieties in genetics, while the genomic basis of CRC and their clinical associations remain poorly understood. Aiming to establish a large genomic and clinical database of patients with colorectal cancer from Chinese population to provide information for early screening and diagnosis, prognostic evaluation, postoperative recurrence monitoring, individualized medication, efficacy evaluation, and drug resistance analysis for patients with CRC, we launched the ChangKang project. Here, as part of the ChangKang Project, we performed ultra-deep whole exome sequencing (WES) of more than 1000 patients with CRC.
Sample scope Multiisolate
Release date 2022-03-11
Publication
PubMed ID Article title Journal name DOI Year
35487942 Comprehensive profiling of 1015 patients' exomes reveals genomic-clinical associations in colorectal cancer Nature Communications 10.1038/s41467-022-30062-8 2022
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 81930065
Natural Science Foundation of Guangdong Province 2014A030312015
Science and Technology Program of Guangdong 2019B020227002
Science and Technology Program of Guangzhou 201904020046
Science and Technology Program of Guangzhou 201803040019
Science and Technology Program of Guangzhou 201704020228
Submitter Rui-hua    Xu  (xurh@sysucc.org.cn)
Organization Sun Yat-sen University
Submission date 2021-03-08

Project Data

Resource name Description
BioSample (2030)  show -