| 项目编号 |
PRJCA004931 |
| 项目标题 |
Pediatric cancer |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Pediatric carcinoma severely threatens children's health with high morbidity and fatality in clinical practice. At present, pathogenesis of various tumors, including neuroblastoma and hepatoblastoma, has been remained unclear. Through single-cell transcriptome sequencing, researchers could draw single-cell atlas of pediatric tumors, identify key regulation molecular and signal pathways responsible for tumor genesis and progression, and therefore speculate potential tumor cellular origin and pathogenesis. Based on these fundamental researches, the study would promote targeted therapy, and ultimately improve clinical prognosis. |
| 样品范围 |
Single cell |
| 发布日期 |
2023-05-25 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 37744240
|
Deciphering pathological behavior of pediatric medullary thyroid cancer from single-cell perspective
|
PeerJ
|
10.7717/peerj.15546
|
2023
|
| 35860547
|
The Cellular and Molecular Landscape of Synchronous Pediatric Sialoblastoma and Hepatoblastoma
|
Frontiers in Oncology
|
10.3389/fonc.2022.893206
|
2022
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82072782
|
|
|
|
| 提交者 |
Rui
Dong (rdong@fudan.edu.cn)
|
| 提交单位 |
Children's Hospital of Fudan University |
| 提交日期 |
2021-01-28 |
