| Accession |
PRJCA004975 |
| Title |
Osteoimmunomodulation of BMSCs on the biomimetic surfaces |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Mus musculus
|
| Description |
Besides monocytes-differentiated MΦs to sites of inflammation, bone marrow-derived inflammatory and tissue-resident MΦs either play a pivotal role in the inflammatory process. That is, intimate crosstalk between BMSCs and MΦs occurs inevitably in the bone microenvironment. However, little is known whether the materials-manipulated BMSCs behavior can impact the immune response of MΦs and the underlying mechanism is unraveled heretofore. Accordingly, MΦs were incubated in CM-BMSC to investigate its impact on osteoimmomudulation through RNA-Seq. |
| Sample scope |
Monoisolate |
| Release date |
2021-05-30 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 34628191
|
A micro/nano-biomimetic coating on titanium orchestrates osteo/angio-genesis and osteoimmunomodulation for advanced osseointegration
|
Biomaterials
|
10.1016/j.biomaterials.2021.121162
|
2021
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| No funding support
|
|
|
|
|
|
| Submitter |
Long
Bai (bailong2012@163.com)
|
| Organization |
East China University of Science and Technology |
| Submission date |
2021-05-08 |
