| Accession |
PRJCA004981 |
| Title |
PRAD single-cell |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
To systematically explore genomic and transcriptomic intra-tumoral heterogeneity cooperate to shape the evolutionary course of prostate cancer ecosystem in primary tumor of un-treated PCa patients. A total of 14 surgically resected tissue samples were collected from patients with prostate cancer, which pathological type were prostatic acinar adenocarcinoma. No endocrine therapy was conducted on all patients before surgery. Cell capture and cDNA synthesis were carried out in 10X Genomics platform, and then transcriptome sequencing was performed in NovaSeq 6000 platform after meeting the all quality control. |
| Sample scope |
Single cell |
| Release date |
2022-08-08 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 35322584
|
Single-Cell RNA-seq Reveals a Developmental Hierarchy Super-Imposed Over Subclonal Evolution in the Cellular Ecosystem of Prostate Cancer
|
Advanced Science
|
10.1002/advs.202105530
|
2022
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Chinese Academy of Sciences (CAS)
|
Strategic Priority Research Program of Chinese Academy of Sciences (CAS)
|
XDA16010102
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2018YFC2000100
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2019YFA0110900
|
|
| Chinese Academy of Sciences (CAS)
|
|
QYZDB-SSW-SMC039
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81672541
|
|
|
|
| Submitter |
Weimin
ci (ciwm@big.ac.cn)
|
| Organization |
Beijing Institute of Genomics, Chinese Academy of Sciences |
| Submission date |
2021-05-10 |
