Accession PRJCA005103
Title The reproductive duct microbiome and transcriptome in endometriosis
Relevance Medical
Data types Metagenome
Transcriptome or Gene expression
Organisms Bacteria
Homo sapiens
Description Endometriosis is a common inflammatory disease confusing approximately 10% of childbearing age women around the world. It has been confirmed that the microbiota in the female reproductive duct could influence its surrounding microenvironment in gynecologic disease and during pregnancy. For the study of the relationship between reproductive duct flora and host gene in patients with ovarian endometrioma, 21 patients diagnosed under laparoscopic operation and 23 healthy women in West China Second University hospital were eligible and processed vaginal swabs. Nucleic acid was extracted from the samples of the vaginal swab, endometrium, and endometrioma. Then 16S rRNA amplicon sequencing and transcriptome sequencing were analyzed.
Sample scope Monoisolate
Release date 2021-08-02
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 81822034
Submitter Shengtao    Zhou  (taotaovip2005@163.com)
Organization West China Second University Hospital
Submission date 2021-05-10

Project Data

Resource name Description
BioSample (81)  show -
GSA (1) -
CRA004639 The microbiome analysis of endometriosis