| Accession |
PRJCA005432 |
| Title |
Study on Interrelated and Dynamic Regulation Mechanism of Histone Protein and DNA Modification in Cell Programming and Renovation |
| Relevance |
Model organism |
| Data types |
Epigenomics
Phenotype or Genotype
Raw sequence reads
|
| Organisms |
Mus musculus
|
| Description |
This project mainly studied the key histone protein modification and DNA modification and dynamic regulation mechanism in the decision of stem cells, and the three major projects were set up. (1) revealing the model of DNA methylation and key group protein modification in early embryo development, Dynamic variation law and regulation mechanism for the development of embryonic fate; (2) Identify new episaged genetic modifications and corresponding modified enzyme systems, expounding their mode, regulation and mechanism of stem cell destiny; (3) reveal cell reprogramming Regulation and control mechanism of key group protein modification and DNA modified to stem cell fate in directional differentiation. |
| Sample scope |
Multiisolate |
| Release date |
2021-06-10 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 33311485
|
|
|
|
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
Major Research Plan
|
2016YFA0100400
|
Study on Interrelated and Dynamic Regulation Mechanism of Histone Protein and DNA Modification in Cell Programming and Renovation
|
|
|
| Accessions in other database |
| Accession |
Database name |
| GSE134592
|
NCBI
|
|
|
| Submitter |
Qing-Yuan
Sun (sunqy@ioz.ac.cn)
|
| Organization |
Institute of Zoology, Chinese Academy of Sciences |
| Submission date |
2021-06-10 |
