| 项目编号 |
PRJCA005491 |
| 项目标题 |
Viral-Host Interactome Analysis Reveals Chicken STAU2 Interacts With Non-structural Protein 1 and Promotes the Replication of H5N1 Avian Influenza Virus |
| 涉及领域 |
Agricultural |
| 数据类型 |
Proteomic
|
| 物种名称 |
Gallus gallus
|
| 描述信息 |
As a highly pathogenic influenza virus, H5N1 avian influenza virus (AIV) poses a great threat to poultry production and public health. H5N1 AIV has a small genome and, therefore, relies heavily on its host cellular machinery to replicate. To develop a comprehensive understanding of how H5N1 AIV rewires host cellular machinery during the course of infection, it is crucial to identify which host proteins and complexes come into physical contact with the viral proteins. Here, we utilized affinity purification mass spectrometry (AP-MS) to systematically determine the physical interactions of 11 H5N1 AIV proteins with host proteins in chicken DF1 cells. This dataset facilitates a more comprehensive and detailed understanding of how the host machinery is manipulated during the course of H5N1 AIV infection |
| 样品范围 |
Monoisolate |
| 发布日期 |
2021-09-01 |
| 出版信息 |
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Key R&D Program of China
|
|
2018YFE0128000
|
|
| National Key R&D Program of China
|
|
2020B020222002
|
|
|
|
| 提交者 |
Qiao
Wang (wangqiao01@caas.cn)
|
| 提交单位 |
Institute of Animal Sciences, Chinese Academy of Agricultural Sciences |
| 提交日期 |
2021-06-02 |
