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Accession PRJCA005528
Title WGBS of pituitary adenomas
Relevance Medical
Data types Epigenomics
Raw sequence reads
Organisms Homo sapiens
Description Tumor stiffness has gradually become the most important factor that affects the surgical resection rate in pituitary adenomas. We performed integrated multi-omic analyses to achieve a better understanding of the underlying mechanisms of tumor stiffness and to explore novel medications to transfer the stiff tumors into soft ones. A total of 22 samples, including 11 soft and 11 stiff pituitary adenomas, were enrolled for WGBS analysis.
Sample scope Multiisolate
Release date 2021-06-23
Publication
PubMed ID Article title Journal name DOI Year
35372359 Multi-Omics Investigations Revealed Underlying Molecular Mechanisms Associated With Tumor Stiffness and Identified Sunitinib as a Potential Therapy for Reducing Stiffness in Pituitary Adenomas Frontiers in Cell and Developmental Biology 10.3389/fcell.2022.820562 2022
Grants
Agency program Grant ID Grant title
Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences 2017-I2M-1-001
Submitter Jun    Gao  (gaojpumch@hotmail.com)
Organization Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Submission date 2021-06-18

Project Data

Resource name Description
BioSample (22)  show -