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Accession PRJCA005624
Title Berberine relieves metabolic syndrome in mice by inhibiting gut microbiota disturbance and liver inflammation caused by high-fat food
Relevance Medical
Data types Targeted loci environmental
Organisms mouse gut metagenome
Description This study used SPF-grade C57BL/6J male mice to construct an obese mouse model, and conduct a systematic study on liver tissue pathology, inflammatory factor expression and gut microbiota structure. With the help of bioinformatics technology, we screened the targets of berberine on gut microbiota, and elucidated the molecular mechanism of berberine treating metabolic syndrome through regulating gut microbiota and inflammatory factors.
Sample scope Environment
Release date 2021-06-29
Data provider
Data provider Data provider URL
Jinjin Li http://www.qlnu.edu.cn/
Grants
Agency program Grant ID Grant title
Second Batch of Young Scientific and Innovative Talents Training Project in Songshan Lake High-Tech Zone NA
Submitter Jiajia    Ni  (nijiajia2005@126.com)
Organization Southern Medical University
Submission date 2021-06-29

Project Data

Resource name Description
BioSample (30)  show -
GSA (1) -
CRA004451 Berberine relieves metabolic syndrome in mice by inhibiting gut microbiota disturbance and liver inflammation caused by high-fat food