Accession PRJCA005779
Title Transcriptome analysis of potential pluripotent cells in pigs and Naive Pluripotent stem cell establishment
Relevance Agricultural
Data types Transcriptome or Gene expression
Organisms Sus scrofa
Description The key scientific problem to be solved in this project is: early pig embryos have multiple naive pluripotent states. The specific mechanism for the establishment and maintenance of the naive pluripotency in these cells. Whether the regulation mechanism of pluripotency is suitable for the establishment and maintenance of the naive pluripotent state in vitro. Main research content including the completion of single-cell transcriptome sequencing analysis of porcine early embryos, blastocyst inner cell mass; proposed the establishment and maintenance of candidate core transcription factors for pig naive pluripotency; proposed the establishment of pig naive pluripotency.
Sample scope Single cell
Release date 2021-09-22
Publication
PubMed ID Article title Journal name DOI Year
31914626 Lineage specification and pluripotency revealed by transcriptome analysis from oocyte to blastocyst in pig FASEB J 10.1096/fj.201901818RR 2020
Biomaterial provider Northeast agriculutral university
Grants
Agency program Grant ID Grant title
China National Center for Biotechnology Development National Key Research and Development program of China-Stem cell and Translational Research 2016YFA0100201 Establishment of pig naive pluripotent stem cell line and analysis of its pluripotency regulation mechanism
China National Center for Biotechnology Developmen National Key Research and Development program of China-Stem cell and Translational Research 2016YFA0100200 Establishment of pig naive pluripotent stem cell line and analysis of its pluripotency regulation mechanism
Accessions in other database
Accession Database name
GSE139512 NCBI
Submitter Xiaogang  Yu  Weng  (wengxg@neau.edu.cn)
Organization Northeast Agricultural University
Submission date 2021-07-08

Project Data

Resource name Description
BioSample (91)  show -
GSA (1) -
CRA004560 Single-cell RNA-seq data of porcine early embryos