Accession PRJCA005841
Title BCR is sensitive to immunosuppressive drugs in patients with systemic lupus ery-thematosus
Relevance Medical
Data types immune receptoire sequencing
Organisms Homo sapiens
Description To describe changes in the immune repertoire (IR) under immunosuppressive treat-ments and identify a general correlation between IR changes and the response to immunosuppressants.Overall, our study first reveals that the BCR repertoire is sensitive to immunosup-pressants in patients with SLE and sheds light on personalized therapy for SLE.
Sample scope Multiisolate
Release date 2021-07-15
Publication
PubMed ID Article title Journal name DOI Year
35092307 Systemic lupus erythematosus patients contain B-cell receptor repertoires sensitive to immunosuppressive drugs European Journal of Immunology 10.1002/eji.202149596 2022
Biomaterial provider qianjin lu
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 81972943
National Natural Science Foundation of China (NSFC) 81830097
National Natural Science Foundation of China (NSFC) 61971187
Submitter qianjin    Lu  (qianlu5860@gmail.com)
Organization Second Xiangya Hospital, Central South University
Submission date 2021-07-15

Project Data

Resource name Description
BioSample (20)  show -