Accession PRJCA005863
Title Single-cell Transcriptomic Analysis Reveals the Landscape of Tumor Ecosystems Underlying Initiation and Progression of Papillary Thyroid Carcinoma
Relevance Medical
Data types Exome
Transcriptome or Gene expression
Organisms Homo sapiens
Description The tumor ecosystem of papillary thyroid carcinoma (PTC) is poorly characterized. Using single-cell RNA sequencing, we profiled transcriptomes of 158,577 cells from 11 patients paratumors, localized/advanced tumors, initially-treated/recurrent lymph nodes and radioactive iodine (RAI)-refractory distant metastases, covering comprehensive clinical courses of PTC.
Sample scope Single cell
Release date 2021-07-30
Publication
PubMed ID Article title Journal name DOI Year
34663816 Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma Nature Communications 10.1038/s41467-021-26343-3 2021
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 81772851
National Natural Science Foundation of China (NSFC) 81972501
Submitter Yulong Wang (headneck@126.com)
Organization Fudan University Shanghai Cancer Center
Submission date 2021-07-17

Project Data

Resource name Description
BioSample (27)  show -