Accession |
PRJCA005863 |
Title |
Single-cell Transcriptomic Analysis Reveals the Landscape of Tumor Ecosystems Underlying Initiation and Progression of Papillary Thyroid Carcinoma |
Relevance |
Medical |
Data types |
Exome
Transcriptome or Gene expression
|
Organisms |
Homo sapiens
|
Description |
The tumor ecosystem of papillary thyroid carcinoma (PTC) is poorly characterized. Using single-cell RNA sequencing, we profiled transcriptomes of 158,577 cells from 11 patients paratumors, localized/advanced tumors, initially-treated/recurrent lymph nodes and radioactive iodine (RAI)-refractory distant metastases, covering comprehensive clinical courses of PTC. |
Sample scope |
Single cell |
Release date |
2021-07-30 |
Publication |
PubMed ID |
Article title |
Journal name |
DOI |
Year |
34663816
|
Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma
|
Nature Communications
|
10.1038/s41467-021-26343-3
|
2021
|
|
Grants |
Agency |
program |
Grant ID |
Grant title |
National Natural Science Foundation of China (NSFC)
|
|
81772851
|
|
National Natural Science Foundation of China (NSFC)
|
|
81972501
|
|
|
Submitter |
Yulong
Wang (headneck@126.com)
|
Organization |
Fudan University Shanghai Cancer Center |
Submission date |
2021-07-17 |