| 项目编号 |
PRJCA005902 |
| 项目标题 |
Human keratoconus m6A study |
| 涉及领域 |
Medical |
| 数据类型 |
Epigenomics
Arraystar Epitranscriptomic microarray
|
| 物种名称 |
Homo
|
| 描述信息 |
Keratoconus (KC) is an asymmetric, progressive ectasia that can lead to severe visual impairment. Despite the high prevalence of the disease, the molecular mechanisms underlying the disease are poorly understood. Here, we analyzed tissues from normal and KC corneas by m6a microarray. Our data showed that the level of m6a modification was significantly altered in cone corneas compared to controls, while KC showed increased inflammation. In conclusion, our corneal tissue data in steady state and disease states provide a unique resource for identifying genes that may contribute to KC and for better understanding and treatment of KC. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2023-07-20 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Academic Promotion Programme of Shandong First Medical University
|
|
2019RC009
|
|
| The Taishan Scholar Foundation of Shandong Province
|
|
201812150
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82070923
|
|
|
|
| 提交者 |
Hua
Gao (hgao@sdfmu.edu.cn)
|
| 提交单位 |
Shandong First Medical University |
| 提交日期 |
2021-07-19 |
