项目编号 PRJCA006001
项目标题 Aberrant gut-metabolome-immune network in schizophrenia
涉及领域 Medical
数据类型 Metagenome
物种名称 human gut metagenome
描述信息 Although schizophrenia (SCZ) has been associated with dramatic changes in the gut microbiome and serum metabolome, the molecular interface between the host and microbiota is poorly understood. To address this, we performed an integrative analysis of intestinal microbiota, serum metabolome, and serum inflammatory cytokines in SCZ patients and controls using a multi-omics strategy. Sixty-three SCZ patients and 57 healthy controls were enrolled in the study. Liquid chromatography-mass spectrometry and bead-based multiplex cytokine assays were performed simultaneously on serum samples, and shotgun metagenomic sequencing was used to evaluate the gut microbial composition and functional potential.
样品范围 Multispecies
发布日期 2021-08-04
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
35309369 Multi-Omics Analysis Reveals Aberrant Gut-Metabolome-Immune Network in Schizophrenia Frontiers in Immunology 10.3389/fimmu.2022.812293 2022
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) 81771471
提交者 Yajuan Fan (1591582705@qq.com)
提交单位 The First Affiliated Hospital of Xi'an Jiaotong University
提交日期 2021-08-01

项目包含数据信息

资源名称 描述
BioSample (120)  show -
GSA (1) -
CRA004662 Aberrant gut-metabolome-immune network in schizophrenia