Accession | PRJCA006196 | ||||||||||||||||||||||||
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Title | Single-cell dissection and mechanisms of hematopoietic reconstitution after allogeneic peripheral blood stem cell transplantation in aplastic anemia | ||||||||||||||||||||||||
Relevance | Medical | ||||||||||||||||||||||||
Data types |
Exome
Transcriptome or Gene expression Raw sequence reads Single cell sequencing |
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Organisms | Homo sapiens | ||||||||||||||||||||||||
Description | We performed single-cell RNA sequencing in 10 aplastic anemia patients who received allogeneic peripheral blood stem cell transplantation. We captured the transcriptional snapshot of transplanted hematopoietic stem and progenitor cells along with total nucleated cells, filled the investigative gaps in human transplantation and improved the understanding regulatory mechanisms of transplanted hematopoietic stem and progenitor cells. | ||||||||||||||||||||||||
Sample scope | Single cell | ||||||||||||||||||||||||
Release date | 2023-03-01 | ||||||||||||||||||||||||
Grants |
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Submitter | Tao Cheng (chengtao@ihcams.ac.cn) | ||||||||||||||||||||||||
Organization | Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences | ||||||||||||||||||||||||
Submission date | 2021-08-16 |
Resource name | Description |
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BioSample (135) show | - |