Accession PRJCA006196
Title Single-cell dissection and mechanisms of hematopoietic reconstitution after allogeneic peripheral blood stem cell transplantation in aplastic anemia
Relevance Medical
Data types Exome
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
Organisms Homo sapiens
Description We performed single-cell RNA sequencing in 10 aplastic anemia patients who received allogeneic peripheral blood stem cell transplantation. We captured the transcriptional snapshot of transplanted hematopoietic stem and progenitor cells along with total nucleated cells, filled the investigative gaps in human transplantation and improved the understanding regulatory mechanisms of transplanted hematopoietic stem and progenitor cells.
Sample scope Single cell
Release date 2023-03-01
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 82070193
National Key Research and Development Program of China 2016YFA0100600
National Key Research and Development Program of China 2018YFA0107801
National Natural Science Foundation of China (NSFC) 81421002
CAMS Initiative for Innovative Medicine 2016-I2M-1-017
Submitter Tao Cheng (chengtao@ihcams.ac.cn)
Organization Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences
Submission date 2021-08-16

Project Data

Resource name Description
BioSample (135)  show -